Shimane Journal of Medical Science

Shimane University Faculty of Medicine
ISSN :0386-5959(in print)
ISSN :2433-2410(online)

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Shimane Journal of Medical Science 9 1
1985-11-01 発行

The Effects of Cadmium on the Adhesion and Growth of Normal and Malignant Human Cells at High Temperatures

Kishimoto, Takuji
Okazaki, Miyoko
Fukuzawa, Yoichiro
Tada, Manabu
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The effects of heat and cadmium (Cd) treatment on the adhesion and subsequent growth of normal (HAIN-55) and malignant (HeLa S3 and HGC-27) human cultured cells were investigated. When malignant human cells were preincubated with 2.0ppm Cd, damage of the so-treated cells was temperature-dependent. In contrast, the subsequent growth of HAIN-55 cells was not affected by Cd treatment at high temperatures. There was no effect of 2.0ppm Cd on the adhesiveness of normal and malignant human cells at high temperatures. Compared with findings in malignant cells, the adhesive function and growth of normal human cells were markedly less sensitive to a high temperature or Cd.