Shimane Journal of Medical Science

Shimane University Faculty of Medicine
ISSN :0386-5959(in print)
ISSN :2433-2410(online)

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Shimane Journal of Medical Science 34 2
2017-12-31 発行

The Accuracy of a Non-invasive Liver Fibrosis Evaluation Method, Shear Wave Elastography: A Retrospective Pilot Study

Kotani, Satoshi Shimane Prefectural Central Hospital
Sato, Shiyuichi Department of Gastroenterology and Hepatology
Kohge, Naruaki Shimane Prefectural Central Hospital
Tsukano, Kosuke Shimane Prefectural Central Hospital
Ogawa, Sayaka Shimane Prefectural Central Hospital
Yamanouchi, Satoshi Shimane Prefectural Central Hospital
Kusunoki, Ryusaku Shimane Prefectural Central Hospital
Aimi, Masahito Shimane Prefectural Central Hospital
Miyaoka, Yoichi Shimane Prefectural Central Hospital
Fujishiro, Hirofumi Shimane Prefectural Central Hospital
Yamamoto, Tomohiko Shimane Prefectural Central Hospital
Ohnuma, Hideyuki Shimane Prefectural Central Hospital
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Description
Objective: We aimed to evaluate the diagnostic accuracy
of shear wave elastography( SWE) for the assessment
of liver fibrosis in patients with liver disease.
Methods: A total of 54 consecutive patients who underwent
SWE measurement and liver biopsy were included.
Receiver-operator characteristic (ROC) curves
were constructed to calculate the area under the ROC
curve( AUC) for F0-2 versus F3-4 and F0-3 versus F4.
Results: Fibrosis scores estimated by SWE were F0 for
9 cases, F1 for 18 cases, F2 for 11 cases, F3 for 9 cases,
and F4 for 7 cases. AUCs for severe fibrosis (F3 and
F4) and cirrhosis (F4) were 0.931 (P < 0.001) and
0.916 (P < 0.001), respectively. Shear wave velocity
correlated significantly with liver fibrosis obtained by
liver biopsy( r = 0.679, P < 0.001).
Conclusion: SWE is a useful and non-invasive technology
to estimate liver fibrosis in liver disease regardless
of etiology.
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Faculty of Medicine, Shimane University