Shimane Journal of Medical Science

Shimane University Faculty of Medicine
ISSN :0386-5959(in print)
ISSN :2433-2410(online)

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Shimane Journal of Medical Science 2 1
1978-09-01 発行

Induction of Tyrosine Aminotransferase by Cholate

Tanigawa, Yoshinori
Kawamura, Masao
Kitamura, Akihide
Miyake, Yoshiyuki
Shimoyama, Makoto
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Description
The intraperitoneal injection of cholate (10 ㎎ per 100 g body weight) to rats elevated the hepatic cyclic AMP levels by 1.5 to 2.0-fold. Furthermore, the hepatic tyrosine aminotransferase was induced by this agent in the both intact and adrenalectomized rats. These data together with previous findings (ref.4) contribute to an understanding of so-called permissive effect produced by glucocorticoids on cyclic AMP mediated process.
NCID
AA00841586