Shimane Journal of Medical Science

Shimane University Faculty of Medicine
ISSN :0386-5959(in print)
ISSN :2433-2410(online)

Creative Commons License
These article are licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
number of downloads : ?
Shimane Journal of Medical Science 19 1
2001-06-01 発行

Production of hepatocyte growth factor in various rat organs

Ishihara, Shunji
Kazumori, Hideaki
Kawashima, Kousaku
Miyaoka, Youichi
Kadowaki, Yasunori
Sato, Hiroshi
Rumi, Mohammad A.K.
Ortega Cava, Cesar F.
Adachi, Kiyoichi
Fukuda, Ryo
Shiozawa, Shunichi
File
Description
The production and content of hepatocyte growth factor (HGF) in various organs has not been fully investigated. In this study, mRNA and immunoreactive material (IRM) for HGF were investigated in order to speculate its role in various organs. Nineteen organs from adult Sprague-Dawley rats were excised and the contents of their mRNA and IRM for HGF were measured. They varied among various organs, found to be highest in the liver, Iung, and kidney. Although the gastrointestinal tract showed a modest expression of HGF, they were undetectable in the testis, skin, or skeletal muscle.