Clinical advantage of terbutaline sulfate (Bricanyl^[○!R]) was evaluated for four patients with anastomotic leakage after gastric operation. Terbutaline sulfate was administered subcutaneously or intravenously for the purpose of inhibiting exocrine pancreatic secretion during a few weeks just after anastomotic leakage was recognized. After this treatment, the injured anastomosis was completely healed and no surgical treatment was not necessitated in all cases. In conclusion terbutaline sulfate is useful for anastomotic leakage after gastric operation.