Bulletin of the Faculty of Agriculture, Shimane University

Faculty of Agriculture, Shimane University

ISSN:0370-940X

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Use this link to cite this item : https://ir.lib.shimane-u.ac.jp/1823

Bulletin of the Faculty of Agriculture, Shimane University 19

1985-12-20 発行

チアミンアナログの生物活性

The Bioactivities of Thiamine Analogues

Mochida, Kazuo

Nakamura, Toshiie

Ozoe, Yoshihisa

Miyazaki, Hisako

Yokouchi, Takayuki

Saito, Osamu

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The bioactive properties of ten kinds of(2-methyl-4-amino-5-pyrimidinyl) methyl derivatives (Pm derivatives) prepared by the base-exchange reaction of immobilized or free thiaminase I were examined.
The insecticidal and sterilizing activities to housefly and the growth regulating activity to common cutworm were not found. However, the herbicidal activity of Pm-o- aminothiophenol to barnyard grass, the antibacterial activity of Pm-nicotinamide to L. fermentum, and the growth inhibitory activity of Pm-aniline, Pm-quinoline and Pm-piperidine to phytoplankton were found. Particularly, the antialgal activity was excellent and selective : Pm-aniline and Pm-quinoline were effective only to diatoms and Pm-piperidine was effective only to blue algae.

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