島根大学農学部研究報告

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島根大学農学部研究報告 19
1985-12-20 発行

チアミンアナログの生物活性

The Bioactivities of Thiamine Analogues
持田 和男
中村 利家
尾添 嘉久
宮崎 久子
横内 孝行
斎藤 修
ファイル
内容記述(抄録等)
The bioactive properties of ten kinds of(2-methyl-4-amino-5-pyrimidinyl) methyl derivatives (Pm derivatives) prepared by the base-exchange reaction of immobilized or free thiaminase I were examined.
The insecticidal and sterilizing activities to housefly and the growth regulating activity to common cutworm were not found. However, the herbicidal activity of Pm-o- aminothiophenol to barnyard grass, the antibacterial activity of Pm-nicotinamide to L. fermentum, and the growth inhibitory activity of Pm-aniline, Pm-quinoline and Pm-piperidine to phytoplankton were found. Particularly, the antialgal activity was excellent and selective : Pm-aniline and Pm-quinoline were effective only to diatoms and Pm-piperidine was effective only to blue algae.