This paper deals with the results of preliminary observations by means of electron microscope on the cell wall structure of potato leaves. Submicroscopic cellulose fibrils i.e. microfibrils was determined by observing the surface replica in two-step method (ethylmetacrylate-carbon and Cr-shadowed). The specimens were observed by J. E. M.7 electron microscope. Some specimens were treated with ethyl alcohol or toluene before the surface replica was observed. Some photographs of microfibrilar orientation of cell wall structure in potato petiole epidermis(Variety Norin No.1) in healthy condition were shown in this paper.