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Shimane journal of medical science 2 巻 1 号
1978-09-01 発行
Induction of Tyrosine Aminotransferase by Cholate
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The intraperitoneal injection of cholate (10 ㎎ per 100 g body weight) to rats elevated the hepatic cyclic AMP levels by 1.5 to 2.0-fold. Furthermore, the hepatic tyrosine aminotransferase was induced by this agent in the both intact and adrenalectomized rats. These data together with previous findings (ref.4) contribute to an understanding of so-called permissive effect produced by glucocorticoids on cyclic AMP mediated process.
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