Internal Tandem Duplication in FLT3 Attenuates Proliferation and Regulates Resistance to the FLT3 Inhibitor AC220 by Modulating p21(Cdkn1a) and Pbx1 in Hematopoietic Cells

number of downloads : ?

Use this link to cite this item : https://ir.lib.shimane-u.ac.jp/53489

language	eng
Author	Abe Mariko Department of Pediatrics, Shimane University School of Medicine, Izumo, Shimane, Japan Pelus Louis M. Department of Microbiology/Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America Singh Pratibha Department of Microbiology/Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America Hirade Tomohiro Department of Pediatrics, Shimane University School of Medicine, Izumo, Shimane, Japan ONISHI, Chie Purevsuren Jamiyan Department of Pediatrics, Shimane University School of Medicine, Izumo, Shimane, Japan Taketani, Takeshi Yamaguchi Seiji Department of Pediatrics, Shimane University School of Medicine, Izumo, Shimane, Japan FUKUDA, Seiji
Journal Title	PLOS ONE
Volume	11
Issue	7
ISSN	1932-6203
Published Date	2016-07-7
DOI	10.1371/journal.pone.0158290
PubMed ID	27387666
Publisher	PUBLIC LIBRARY SCIENCE
NII Type	Journal Article
OAI-PMH Set	Faculty of Medicine
Remark	Support was provided by: Japan Society for the Promotion of Science [https://www.jsps.go.jp/] grant number 24791063 to MA; National Heart Lung and Blood Institute [http://www.nih.gov/] grant number HL079654 to LP; Japan Society for the Promotion of Science [https://www.jsps.go.jp/] grant number 20390298 to SF; Japan Society for the Promotion of Science [https://www.jsps.go.jp/] grant number 25461593 to SF; Japan Leukemia Research Fund [http://flrf.gr.jp/] to SF; Research Support Funds from the Mochida Memorial Foundation for Medical and Pharmaceutical Research [http://www.mochida.co.jp/zaidan/] to SF; Sankyo Biomedical Research Foundation and the Mitsubishi Pharma Research Foundation [http://www.ds-fdn.or.jp/] to SF; AstraZeneca Research Grant [http://www. astrazeneca.co.jp/] to SF; Naito Foundation [https://www.naito-f.or.jp/jp/index.php] to SF. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.