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language
eng
Attribute
Case Report
Author
YAMAGISHI, Mutsumi
UNO, Masafumi
NAGANO, Natsuko
NAGAMI, Taichi
Description
An 80-year-old man received salvage radiation therapy for prostate-specific antigen recurrence of prostate cancer after prostatectomy. Urinary retention and edema of both legs developed 1 year and 3 months after initiation of radiation therapy. Imaging showed significant fibrosis in the radiation field. Histological findings were characteristic of ischemic changes, but not retroperitoneal fibrosis or fibrosarcoma. Development of significant fibrosis with accompanying symptoms after postoperative radiation therapy is rare in prostate cancer. The patient’s history of heavy smoking and arteriosclerotic diseases ( e.g., cerebral infarction and carotid artery stenosis ), in addition to an elevated D-dimer level confirmed by blood test, suggested the presence of underlying advanced vascular endothelial disorders and microvascular circulatory disorders. Significant fibrosis was likely caused by the patient’s underlying condition in addition to surgery and extensive radiation to the pelvis.
Subject
prostate cancer
postoperative
prostatespecific antigen recurrence
salvage radiotherapy
Journal Title
Shimane Journal of Medical Science
Volume
38
Issue
1
Start Page
33
End Page
38
ISSN
03865959
ISSN(Online)
24332410
Published Date
2021-03
NCID
AA00841586
DOI
DOI(SelfDOI)
Publisher
Faculty of Medicine, Shimane University
Publisher Aalternative
島根大学医学部
NII Type
Departmental Bulletin Paper
Format
PDF
Rights
Faculty of Medicine, Shimane University
Text Version
出版社版
OAI-PMH Set
Faculty of Medicine
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