| Title Transcription | コウソテキ エンキ コウカン ハンノウ オ リヨウシタ チアミン アナログ ノ チョウセイ
|
| Title Alternative (English) | Enzymic Preparation of Thiamine Analogues by the Utilization of a Base-Exchange Reaction
|
| File | |
| language |
jpn
|
| Author |
Mochida, Kazuo
Nakamura, Toshiie
Fujita, Keiji
|
| Description | The enzymic preparation of thiamine analogues was examined. Thiaminase I catalyzes an exchange reaction of the thiazole moiety of thiamine with aniline, pyridine, cysteine etc., liberating 2-hydroxyalkyl-4-methyl-5-β-hydroxyethylthiazole. Ten kinds of（2-methyl -4-amino-5-pynmidinyl）methyl derivatives(Pm derivatives) were preparated by the uti lization of the base-exchange reaction of free or Sepharose 4B-immobilized thiaminase I. Pm derivatives isolated were Pm-thiophenol, Pm-o-aminothiophenol, Pm-benzoic acid, Pmaniline, Pm-pyridine, Pm-α-pycoline, Pm-nicotinamide, Pm-quinoline, Pm-pyperidine, and Pm-cysteine. The physicochemical parameters of these compounds were determined.
|
| Journal Title |
Bulletin of the Faculty of Agriculture, Shimane University
|
| Volume | 18
|
| Start Page | 188
|
| End Page | 192
|
| ISSN | 0370940X
|
| Published Date | 1984-12-20
|
| NCID | AN00108015
|
| Publisher | 島根大学農学部
|
| Publisher Aalternative | Shimane University, Faculty of Agriculture
|
| NII Type |
Departmental Bulletin Paper
|
| OAI-PMH Set |
Faculty of Life and Environmental Science
|
| 他の一覧 |
