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language
eng
Author
Masumura, Sumio
Hashimoto, Michio
Takeda, Isamu
Description
We studied the effects of angiotensin II on the level of plasma insulin and on the activity of liver glycogen phosphorylase, during the hyperglycemic response to this polypeptide in rabbits. The activity of liver glycogen phosphorylase increased during the initial stages of hyperglycemia and the peak was observed at 10min after the injection of this polypeptide. However, with the elapse of time, the activity decreased and recovered to the control level. The level of plasma immunoreactive insulin (IRI) was unaffected by angiotensin II during the initial stages at 0-40min and increased, when the level of blood glucose attained the maximum at 60min. Moreover the elevated level continued for 20min. Under such conditions, blood glucose appears to be gradually restored to the control level by the increase in IRI.
Subject
angiotensin II
glycogen phosphorylase
immunoreactive insulin
Journal Title
Shimane journal of medical science
Volume
5
Issue
1
Start Page
81
End Page
84
ISSN
03865959
ISSN(Online)
24332410
Published Date
1981-06-01
NCID
AA00841586
Publisher Aalternative
Shimane Medical University
NII Type
Departmental Bulletin Paper
Format
PDF
Text Version
出版社版
Gyoseki ID
e28099
OAI-PMH Set
Faculty of Medicine
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