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language
eng
Attribute
original article
Author
Liang Shuai
Tanabe, kazuaki
Niu Yang
Description
Histological changes of human fetal hearts wereobserved in fetuses from the 3rd to 7th month ofgestation to analyze the myocardium, endocardium, and epicardium as well as Purkinje fiber cells. In the 3rd month, cardiac muscle cells were irregular in shape and arrangement. In the 7th month, they were more homogenous in shape, longer than in
3rd month, and typically arranged in parallel. These changes became evident from the 6th month, and by the 7th month their histological features had become almost the same as those in adults. There were no significant regional differences in the morphology of
the cardiomyocytes among the parts of the heart. In both the endocardium and picardium, a relatively rich underlying connective tissue layer was observed in the 3rd month, whereas it decreased significantly thereafter. Subendocardial Purkinje fibers were not
clearly identified in the 3rd month, but they wereidentified from the 4th month. The present findingsshow normal morphological development of human fetal heart and suggest the corresponding functional maturation.
Subject
Human fetus
cardiac muscle cell
Purkinje fiber
endocardium
epicardium
histology
Journal Title
Shimane journal of medical science
Volume
30
Issue
1
Start Page
1
End Page
10
ISSN
03865959
ISSN(Online)
24332410
Published Date
2013-11-01
NCID
AA00841586
Publisher
Shimane University Faculty of Medicine
NII Type
Departmental Bulletin Paper
Format
PDF
Text Version
出版社版
Gyoseki ID
e21992
OAI-PMH Set
Faculty of Medicine
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