The inverted type of papilloma extensively distributed to nasal and paranasal sinus mucosae has been well known to be frequently coupled with squamous cell carcinoma. Therefore, the diagnostic procedure and treatment strategy of patients with inverted type of papilloma should be much more carefully designed and performed rather than those with exophytic type of papilloma. Otherwise, the poor prognosis must be unavoidable. Herein, the pathological feature and standard clinical management of this
disease entity are introduced and discussed, based on our experience with 11 cases.