KN3014, a piperidine-containing small compound, inhibits auto-secretion of IL-1 beta from PBMCs in a patient with Muckle-Wells syndrome

SCIENTIFIC REPORTS 10 巻 1 号 2020-08-11 発行
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タイトル
KN3014, a piperidine-containing small compound, inhibits auto-secretion of IL-1 beta from PBMCs in a patient with Muckle-Wells syndrome
著者
Kaneko Naoe
Kurata Mie
Yamamoto Toshihiro
Shigemura Tomonari
Agematsu Kazunaga
Yamazaki Takashi
Takeda Hiroyuki
Sawasaki Tatsuya
Koga Tomohiro
Kawakami Atsushi
Yachie Akihiro
Migita Kiyoshi
Yoshiura Koh-ichiro
Masumoto Junya
収録物名
SCIENTIFIC REPORTS
10
1
収録物識別子
ISSN 2045-2322
言語
英語
資源タイプ 学術雑誌論文
出版者
NATURE PUBLISHING GROUP
発行日 2020-08-11
アクセス権 メタデータのみ
関連情報
[DOI] 10.1038/s41598-020-70513-0
[PMID] 32782316
備考 We thank the Division of Laboratory Animal Research of the Advanced Research Support Center (ADRES), Ehime University for technical assistance. This work was supported by JSPS KAKENHI, Grant Numbers JP17H04656 and JP17K19685 (to J.M.), and JP16H00609, JP17H00599, and JP18H00464 (to N.K.), and by the Center for Clinical and Translational Research of Kyushu University Hospital. This work was also supported by Platform for Drug Discovery, Informatics, and Structural Life Science from Japan Agency for Medical Research and Development (AMED).