Existence regions of positive periodic solutions for a discrete hematopoiesis model with unimodal production functions

Applied Mathematical Modelling Volume 68 Page 152-168 published_at 2019-04
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Title
Existence regions of positive periodic solutions for a discrete hematopoiesis model with unimodal production functions
Creator
Yan Yan
Source Title
Applied Mathematical Modelling
Volume 68
Start Page 152
End Page 168
Journal Identifire
ISSN 0307-904X
Descriptions
A discrete model describing the increase and decrease of blood cells is considered in this
paper. This hematopoiesis model is a discretization of a delay differential equation with
unimodal production function whose coefficients and delay are periodic discrete functions
with ω-period. This paper is concerned with the existence of positive ω-periodic solutions.
Our results are proved by using the well-known continuation theorem of coincidence degree
theory. The existence range of the positive ω-periodic solutions is also clarified. A
concrete example and its simulation are also given to illustrate our result. Finally, we
examine how positive numbers and coefficients making up our model influence the upper
and lower limits of blood cell counts.
Subjects
Discrete hematopoiesis model ( Other)
Unimodal production function ( Other)
Positive periodic solutions ( Other)
Existence Region ( Other)
Continuation theorem ( Other)
Language
eng
Resource Type journal article
Publisher
Elsevier
Date of Issued 2019-04
Publish Type Accepted Manuscript
Access Rights open access
Relation
[DOI] 10.1016/j.apm.2018.11.003