number of downloads : ?
File
language
eng
Author
Naito, Atsushi
Tamura, Katsuhiro
Nakase, Akira
Description
As a surgical method for the treatment of unresectable hepatocellular carcinoma (HCC), we developed a new therapy which consists of intermittent hepatic arterial occlusion (IHAO) during infusion chemotherapy by the use of double lumen balloon catheter inserted into the hepatic artery. This therapy was performed in 23 cases with unresectable HCC. Antineoplastic effects judged by Karnofsky's criteria were I-B in 19,I-A in three and 0-0 in one case. It was proved that the anticancer drug remained for a longer period at higher concentrations in the liver during IHAO. With the advance of gradual induction of thrombosis from peripheral hepatic artery by frequent HAO, liver dysfunction, growth of collateral vessels and repatency after induction of thrombosis could be suppressed. We conclude that this new therapy is a safe and more effective procedure for unresectable HCC and will have a wide application.
Subject
intermittent hepatic arterial occlusion
infusion chemotherapy
double lumen catheter
unresectable hepatocellular carcinoma
Journal Title
Shimane journal of medical science
Volume
13
Start Page
23
End Page
37
ISSN
03865959
ISSN(Online)
24332410
Published Date
1992
NCID
AA00841586
Publisher Aalternative
Shimane Medical University
NII Type
Departmental Bulletin Paper
Format
PDF
Text Version
出版社版
OAI-PMH Set
Faculty of Medicine
他の一覧