Transmitochondrial mice as models for primary prevention of diseases caused by mutation in the tRNA(Lys) gene

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Use this link to cite this item : https://ir.lib.shimane-u.ac.jp/53742

language	eng
Author	Shimizu Akinori Faculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba Mito Takayuki Faculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba Hayashi Chisato Faculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba Ogasawara Emi Faculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba Koba Ryusuke Faculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba Negishi Issei Faculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba Takenaga, Keizo Nakada Kazuto Faculty of Life and Environmental Sciences and International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8572, Japan Hayashi Jun-Ichi Faculty of Life and Environmental Sciences and International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8572, Japan
Subject	mutated mtDNA segregation; mtDNA heteroplasmic mutation; preimplantation genetic diagnosis; selection of oocytes
Journal Title	PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume	111
Issue	8
Start Page	3104
End Page	3109
ISSN	0027-8424
Published Date	2014-02-25
DOI	10.1073/pnas.1318109111
PubMed ID	24510903
Publisher	NATL ACAD SCIENCES
NII Type	Journal Article
OAI-PMH Set	Faculty of Medicine
Remark	This work was supported by Grants-in-Aid for Scientific Research A 25250011 (to J.-I.H.), Scientific Research A 23240058 (to K.N.), and Scientific Research on Innovative Areas 24117503 (to J.-I.H.) from the Japan Society for the Promotion of Science. This work was supported also by the World Premier International Research Center Initiative, Ministry of Education, Culture, Sports, Science and Technology-Japan (K.N. and J.-I.H.).