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language
eng
Author
Tanimoto, Kazumasa Department of Chemistry, Graduate School of Natural Science and Technology, Shimane University, 1060 Nishikawatsu, Matsue, 690-8504, Japan
Okai, Hayaki Department of Chemistry, Graduate School of Natural Science and Technology, Shimane University, 1060 Nishikawatsu, Matsue, 690-8504, Japan
Oka, Marina Department of Chemistry, Graduate School of Natural Science and Technology, Shimane University, 1060 Nishikawatsu, Matsue, 690-8504, Japan
Ohkado, Ryoma Department of Chemistry, Graduate School of Natural Science and Technology, Shimane University, 1060 Nishikawatsu, Matsue, 690-8504, Japan
Description
The aerobic oxidative cross-coupling of indoles with azoles driven by flavin-iodine-coupled organocatalysis has been developed for the green synthesis of 2-(azol-1-yl)indoles. The coupled organocatalytic system enabled the one-pot three-component synthesis of 2-azolyl-3-thioindoles from indoles, azoles, and thiols in an atom-economical manner by utilizing molecular oxygen as the only sacrificial reagent.
Subject
Oxidation reactions
Flavins
Chemical synthesis,Indoles
Cross coupling reaction
Journal Title
Organic Letters
Volume
23
Issue
6
Start Page
2084
End Page
2088
ISSN
1523-7060
ISSN(Online)
1523-7052
Published Date
2021-03-19
DOI
Publisher
American Chemical Society
NII Type
Journal Article
Format
PDF
Text Version
著者版
Gyoseki ID
38962
OAI-PMH Set
Faculty of Science and Engineering