File
language
eng
Author
Tamura-Nakano, Miwa
Nakaya, Fumio
Iida, Tomohiro
Iwata, Yoko
Description
Spermatozoa released by males should remain viable until fertilization. Hence, sperm longevity is governed by intrinsic and environmental factors in accordance with the male mating strategy. However, whether intraspecific variation of insemination modes can impact sperm longevity remains to be elucidated. In the squid Heterololigo bleekeri, male dimorphism (consort and sneaker) is linked to two discontinuous insemination modes that differ in place and time. Notably, only sneaker male spermatozoa inseminated long before egg spawning can be stored in the seminal receptacle. We found that sneaker spermatozoa exhibited greater persistence in fertilization competence and flagellar motility than consort ones because of a larger amount of flagellar glycogen. Sneaker spermatozoa also showed higher capacities in glucose uptake and lactate efflux. Lactic acidosis was considered to stabilize CO2-triggered self-clustering of sneaker spermatozoa, thus establishing hypoxia-induced metabolic changes and sperm survival. These results, together with comparative omics analyses, suggest that postcopulatory reproductive contexts define sperm longevity by modulating the inherent energy levels and metabolic pathways.
Journal Title
Journal of biological chemistry
Volume
291
Issue
37
Start Page
19324
End Page
19334
ISSN
00219258
Published Date
2016-09-09
DOI
DOI Date
2016-12-14
PubMed ID
NCID
AA00251083
Publisher
American Society for Biochemistry and Molecular Biology
NII Type
Journal Article
Format
PDF
Rights
This research was originally published in 'Journal of biological chemistry'. Noritaka Hirohashi, Miwa Tamura-Nakano, Fumio Nakaya, Tomohiro Iida and Yoko Iwata. Sneaker Male Squid Produce Long-lived Spermatozoa by Modulating Their Energy Metabolism. Journal of biological chemistry. 2016; 291:19324-19334. © the American Society for Biochemistry and Molecular Biology
Text Version
著者版
OAI-PMH Set
Education and Research Center for Biological Research, Faculty of Life and Environmental Science