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language
eng
Author
Tadenuma, Saki Department of Anesthesiology, Faculty of Medicine, Shimane University, Shimane
Kanda, Hideyuki Department of Environmental Health and Public Health, Faculty of Medicine, Shimane University
Ishikawa, Shizukiyo Center for Community Medicine, Jichi Medical University
Kayaba, Kazunori Graduate School of Saitama Prefectural University
Gotoh, Tadao Wara National Health Insurance Clinic, Gifu
Nakamura, Yosikazu Department of Public Health, Jichi Medical University
Kajii, Eiji Center for Community Medicine, Jichi Medical University
Description
Dietary salt intake has been reported to be associated with cardiovascular disease (CVD). However, there were few studies that assessed the relationship of salt preference with CVD. We examined the association between salt preference and the incidence of CVD and its subtypes in a Japanese general population. Based on the prospective Jichi Medical School Cohort Study, data were analyzed from 11,394 eligible participants. A baseline survey of the preference for salt was obtained by questionnaire and health examinations from April 1992 through July 1995 in 12 communities in Japan. The participants were followed up until December 2005 (mean follow-up period, 10.7 ± 2.4 years). Subjects were divided into three categories according to their preference for salt: favor, so-so, and disfavor. A Cox proportional hazards model was used to calculate hazard ratios (HRs) of the incidence of CVD according to the preference categories. We observed 485 cardiovascular events (258 in men and 227 in women). Among the men, the multivariable adjusted HRs for incidence of myocardial infarction and subarachnoid hemorrhage for favor versus so-so salt preference were 0.34 (95% confidence interval, 0.17 - 0.71) and 7.10 (0.88 - 56.84), respectively. Among the women, age-adjusted HRs for the incidence of CVD, total stroke, cerebral hemorrhage, and cerebral infarction for the favor preference were 1.41 (1.02 - 1.95), 1.36 (0.97 - 1.91), 1.79 (0.87 - 3.71), and 1.40 (0.89 - 2.19), respectively. The data indicated that preference for salt may be associated with an increase in the incidence of CVD in women.
Subject
Salt Preference
Cardiovascular Disease
Cohort Study
Japanese
Journal Title
Health
Volume
8
Issue
1
Start Page
105
End Page
115
ISSN
19494998
Published Date
2016-01
DOI
Publisher
Scientific Research Publishing
NII Type
Journal Article
Format
PDF
Rights
Copyright © 2016 by authors and Scientific Research Publishing Inc.
This work is licensed under the Creative Commons Attribution International License (CC BY).http://creativecommons.org/licenses/by/4.0/
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OAI-PMH Set
Faculty of Medicine