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Title Transcription
メダカ コクショク ソホウ ノ カリュウ イドウ ニ オヨボス SH ソガイザイ ノ エイキョウ
Title Alternative (English)
Effects of Sulfhydryl Inhibitors on Migration of Pigment Granules in the Melanophore of Oryzias latipes
File
language
eng
Author
Iga, Tetsuro
Description
The effects of two sulfhydryl inhibitors, Igrosin (containing mersalyl as an effective agent)and N-ethylmaleimide (NEM), were studied on pigment migration in melanophores of Oryziaslatipes. Activities of melanophores were measured photoelectrically and simultaneously confirmedby microscopic observation. Pretreatment with each of these inhibitors at a concentrationof 10^<-3> M blocked completely pigment aggregation within the melanophores to KClor adrenaline. The effects of these agents could not be removed by washing with the physiologicalsolution alone. Cysteine reversed the effects of these inhibitors on the response of melanophoresto KCl or adrenaline. These inhibitors produced dispersion of pigment in punctateadrenaline-treated melanophores which was markedly rapid as compaired with that producedby the saline alone. If one of the inhibitors was applied in combination with adrenalinefollowing temporary pigment aggregation within the melanophores rapid pigment dispersionwas induced. Based on these results, possible involvement of the elements of protein -SHgroups on pigment aggregation mechanism was discussed.
Journal Title
Memoirs of the Faculty of Literature and Science, Shimane University. Natural sciences
Volume
8
Start Page
75
End Page
84
ISSN
03709434
Published Date
1975-03-10
NCID
AN0010806X
Publisher
島根大学文理学部
Publisher Aalternative
The Faculty of Literature and Science, Shimane University
NII Type
Departmental Bulletin Paper
OAI-PMH Set
Faculty of Science and Engineering
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