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File
language
eng
Author
Oguni, Masami
Setogawa, Tomoichi
Tanaka, Osamu
Shinohara, Haruo
Kato, Kanefusa
Description
S-100 protein has two subunits, S-100α and S-100β. S-100α is predominant in neurons and slow-twitch muscle fibers, while S-100β exists in glial cells and Schwann cells. In the present study, the presence of S-100α and S-100β was investigated immunohistochemically in the extraocular muscles of 15 human embryos (Carnegie stages 13 to 23) and in one fetus (10 weeks of gestation). During stages 13-17,no immunoreactivities to S-100α and S-100β were found around the optic vesicle. At stage 18,immunoreactivity to S-100β appeared around the optic vesicles and increased as the embryonic stages advanced. In the fetus, the nerve fibers in the extraocular muscles were slightly immunoreactive to S-100α, but the muscle fibers were not. These findings suggested that extraocular muscles are innervated in the late embryonic period, around stage 18.
Subject
S-100α
S-100β
Neuron-specific enolase
Immunohistochemistry
Extraocular muscles
Human embryos
Journal Title
Shimane journal of medical science
Volume
14
Start Page
7
End Page
10
ISSN
03865959
ISSN(Online)
24332410
Published Date
1996
NCID
AA00841586
Publisher Aalternative
Shimane Medical University
NII Type
Departmental Bulletin Paper
Format
PDF
Text Version
出版社版
OAI-PMH Set
Faculty of Medicine
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