Evaluation of the heterogeneous tissue distribution of erlotinib in lung cancer using matrix-assisted laser desorption ionization mass spectrometry imaging

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Use this link to cite this item : https://ir.lib.shimane-u.ac.jp/53289

language	eng
Author	Tsubata, Yukari Hayashi Mitsuhiro Division of Molecular Pharmacology, National Cancer Center Research Institute, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan Division of Clinical Pharmacology and Translational Research, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan TANINO, Ryosuke Aikawa Hiroaki Division of Clinical Pharmacology and Translational Research, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan Ohuchi Mayu Division of Molecular Pharmacology, National Cancer Center Research Institute, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan Tamura Kenji Department of Breast and Medical Oncology, National Cancer Center Hospital, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan Fujiwara Yasuhiro Department of Breast and Medical Oncology, National Cancer Center Hospital, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan Isobe, Takeshi Hamada Akinobu Division of Molecular Pharmacology, National Cancer Center Research Institute, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan Division of Clinical Pharmacology and Translational Research, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan
Journal Title	SCIENTIFIC REPORTS
Volume	7
ISSN	2045-2322
Published Date	2017-10-3
DOI	10.1038/s41598-017-13025-8
PubMed ID	28974758
Publisher	NATURE PUBLISHING GROUP
NII Type	Journal Article
OAI-PMH Set	Faculty of Medicine
Remark	We thank all the people related to this study including patient and family. We also thank N. Ohtsuka, S. Ryu, T. Yoshino, Y. Murai, M. Mizui, M. Nishidate, and R. Matsukane for their help. This work was supported by grants from the Accelerating Regulatory Science Initiative, Ministry of Health, Labour and Welfare, Japan (Y.F.), the National Cancer Center Development Fund (26-A-20, A.H.), and in part the Project for Cancer Research And Therapeutic Evolution, Japan Agency for Medical Research and Development (16cm0106223h0001, M.H.).