Interethnic analyses of blood pressure loci in populations of East Asian and European descent

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Author	Takeuchi Fumihiko Medical Genomics Center, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan Akiyama Masato These authors contributed equally: Fumihiko Takeuchi, Masato Akiyama, Nana Matoba, Tomohiro Katsuya, Masahiro Nakatochi, Yasuharu Tabara. Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan Matoba Nana These authors contributed equally: Fumihiko Takeuchi, Masato Akiyama, Nana Matoba, Tomohiro Katsuya, Masahiro Nakatochi, Yasuharu Tabara. Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan Katsuya Tomohiro Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan Nakatochi Masahiro Data Coordinating Center, Department of Advanced Medicine, Nagoya University Hospital, Nagoya, 466-8560, Japan Tabara Yasuharu Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan Narita Akira Tohoku Medical Megabank Organization, Tohoku University, Sendai, 980-8573, Japan Saw Woei-Yuh Life Sciences Institute, National University of Singapore, Singapore, 117456, Singapore Moon Sanghoon Division of Genome Research, Center for Genome Science, National Institute of Health, Chungcheongbuk-do, 363-951, Republic of Korea Spracklen Cassandra N. Department of Genetics, University of North Carolina, Chapel Hill, NC 27514, USA Chai Jin-Fang Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, 117549, Singapore Kim Young-Jin Division of Genome Research, Center for Genome Science, National Institute of Health, Chungcheongbuk-do, 363-951, Republic of Korea Zhang Liang Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 168751, Singapore Wang Chaolong Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, 138672, Singapore Duke-NUS Medical School, Singapore, 169857, Singapore Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China Li Huaixing CAS Key Laboratory of Nutrition, Metabolism and Food safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of the Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China Li Honglan State Key Laboratory of Oncogene and Related Genes and Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, China Wu Jer-Yuarn Institute of Biomedical Sciences, Academia Sinica, Taipei, 115, Taiwan School of Chinese Medicine, China Medical University, Taichung, 40402, Taiwan Dorajoo Rajkumar Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, 138672, Singapore Nierenberg Jovia L. Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA Wang Ya Xing Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China He Jing Division of Epidemiology, Vanderbilt University Medical Center, Nashville, TN 37203-1738, USA Bennett Derrick A. Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK Takahashi Atsushi Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan Department of Genomic Medicine, Research Institute, National Cerebral and Cardiovascular Center, Osaka, 565-0873, Japan Momozawa Yukihide Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan Hirata Makoto Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan Matsuda Koichi Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, 277-8561, Japan Rakugi Hiromi Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan Nakashima Eitaro Division of Endocrinology and Diabetes, Department of Internal Medicine, Nagoya University Graduate School of Medicine, Nagoya, 466-8550, Japan Department of Diabetes and Endocrinology, Chubu Rosai Hospital, Nagoya, 455-8530, Japan Isono Masato Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan Shirota Matsuyuki Tohoku Medical Megabank Organization, Tohoku University, Sendai, 980-8573, Japan Hozawa Atsushi Tohoku Medical Megabank Organization, Tohoku University, Sendai, 980-8573, Japan Ichihara Sahoko Department of Environmental and Preventive Medicine, Jichi Medical University School of Medicine, Shimotsuke, 329-0498, Japan Matsubara Tatsuaki Department of Internal Medicine, School of Dentistry, Aichi Gakuin University, Nagoya, 470-0195, Japan Yamamoto Ken Department of Medical Biochemistry, Kurume University School of Medicine, Kurume, 830-0011, Japan Kohara Katsuhiko Faculty of Collaborative Regional Innovation, Ehime University, Matsuyama, 790-8577, Ehime, Japan Igase Michiya Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Toon, 791-0295, Ehime, Japan Han Sohee Division of Genome Research, Center for Genome Science, National Institute of Health, Chungcheongbuk-do, 363-951, Republic of Korea Gordon-Larsen Penny Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, USA Huang Wei Department of Genetics, Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center and Shanghai Industrial Technology Institute (SITI), Shanghai, 201203, China Lee Nanette R. USC-Office of Population Studies Foundation, University of San Carlos, Cebu City, 6000, Philippines Department of Anthropology, Sociology and History, University of San Carlos, Cebu City, 6000, Philippines Adair Linda S. Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, USA Hwang Mi Yeong Division of Genome Research, Center for Genome Science, National Institute of Health, Chungcheongbuk-do, 363-951, Republic of Korea Lee Juyoung Division of Genome Research, Center for Genome Science, National Institute of Health, Chungcheongbuk-do, 363-951, Republic of Korea Chee Miao Li Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 168751, Singapore Sabanayagam Charumathi Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 168751, Singapore Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, 169857, Singapore Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore Zhao Wanting Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 168751, Singapore Duke-NUS Medical School, Singapore, 169857, Singapore Liu Jianjun Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, 138672, Singapore Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597, Singapore Reilly Dermot F. Merck Sharp Dohme Corp, Kenilworth, NJ 07033, USA Sun Liang CAS Key Laboratory of Nutrition, Metabolism and Food safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of the Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China Huo Shaofeng CAS Key Laboratory of Nutrition, Metabolism and Food safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of the Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China Edwards Todd L. Division of Epidemiology, Vanderbilt University Medical Center, Nashville, TN 37203-1738, USA Long Jirong Division of Epidemiology, Vanderbilt University Medical Center, Nashville, TN 37203-1738, USA Chang Li-Ching Institute of Biomedical Sciences, Academia Sinica, Taipei, 115, Taiwan Chen Chien-Hsiun Institute of Biomedical Sciences, Academia Sinica, Taipei, 115, Taiwan Yuan Jian-Min Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA Division of Cancer Control and Population Sciences, UPMC Hillman Cancer, University of Pittsburgh, Pittsburgh, PA 15232, USA Koh Woon-Puay Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, 117549, Singapore Health Services and Systems Research, Duke-NUS Medical School, Singapore, 169857, Singapore Friedlander Yechiel Unit of Epidemiology, Hebrew University-Hadassah Braun School of Public Health, Jerusalem, P.O. Box 12272, Israel Kelly Tanika N. Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA Wei Wen Bin Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China Xu Liang Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China Cai Hui Division of Epidemiology, Vanderbilt University Medical Center, Nashville, TN 37203-1738, USA Xiang Yong-Bing State Key Laboratory of Oncogene and Related Genes and Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, China Lin Kuang Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK Clarke Robert Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK Walters Robin G. Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK Millwood Iona Y. Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK MRC Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK Li Liming Chinese Academy of Medical Sciences, Beijing, 100006, China Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, 100191, China Chambers John C. Department of Epidemiology and Biostatistics, Imperial College London, London, SW7 2AZ, UK Kooner Jaspal S. National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK Elliott Paul Medical Research Council-Public Health England (MRC-PHE) Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, SW7 2AZ, UK Imperial College Biomedical Research Centre, Imperial College London, London, SW7 2AZ, UK UK-Dementia Research Institute at Imperial College London, London, SW7 2AZ, UK National Institute for Health Research (NIHR) Health Protection Research Unit on Health Impacts of Environmental Hazards, London, SW7 2AZ, UK Health Data Research UK-London, London, UK van der Harst Pim Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, Netherlands Chen Zhengming Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK Sasaki Makoto Iwate Tohoku Medical Megabank Organization, Iwate, 028-3694, Japan Shu Xiao-Ou Division of Epidemiology, Vanderbilt University Medical Center, Nashville, TN 37203-1738, USA Jonas Jost B. Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China Department of Ophthalmology, Medical Faculty Mannheim, University Heidelberg, Germany, Mannheim, 68167, Germany He Jiang Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, LA, USA Heng Chew-Kiat Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore Khoo Teck Puat-National University Children’s Medical Institute, National University Health System, Singapore, 119228, Singapore Chen Yuan-Tsong Institute of Biomedical Sciences, Academia Sinica, Taipei, 115, Taiwan Zheng Wei Division of Epidemiology, Vanderbilt University Medical Center, Nashville, TN 37203-1738, USA Lin Xu CAS Key Laboratory of Nutrition, Metabolism and Food safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of the Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China Teo Yik-Ying Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, 117549, Singapore Life Sciences Institute, National University of Singapore, Singapore, 117456, Singapore NUS Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore, 119077, Singapore Tai E-Shyong Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, 117549, Singapore Duke-NUS Medical School, Singapore, 169857, Singapore Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597, Singapore Cheng Ching-Yu Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 168751, Singapore Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, 169857, Singapore Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore Wong Tien Yin Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 168751, Singapore Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, 169857, Singapore Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore Sim Xueling Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, 117549, Singapore Mohlke Karen L. Department of Genetics, University of North Carolina, Chapel Hill, NC 27514, USA Yamamoto Masayuki Tohoku Medical Megabank Organization, Tohoku University, Sendai, 980-8573, Japan Kim Bong-Jo Division of Genome Research, Center for Genome Science, National Institute of Health, Chungcheongbuk-do, 363-951, Republic of Korea Miki Tetsuro Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Toon, 791-0295, Ehime, Japan Nabika, Toru Yokota Mitsuhiro Department of Genome Science, School of Dentistry, Aichi Gakuin University, Nagoya, 464-8650, Japan Kamatani Yoichiro Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan Kyoto-McGill International Collaborative School in Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, 606-8501, Japan Kubo Michiaki RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan Kato Norihiro Medical Genomics Center, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan
Journal Title	NATURE COMMUNICATIONS
Volume	9
ISSN	2041-1723
Published Date	2018-11-28
DOI	10.1038/s41467-018-07345-0
PubMed ID	30487518
Publisher	NATURE PUBLISHING GROUP
NII Type	Journal Article
OAI-PMH Set	Faculty of Medicine