Adenosine deaminase acting on RNA-1 (ADAR1) inhibits hepatitis B virus (HBV) replication by enhancing microRNA-122 processing

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language	eng
Author	Liu Guangyan 1College of Basic Medical Sciences, Shenyang Medical College, Shenyang 110034, China. 2Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, Guangdong, China. 3Department of Molecular Genetics, Kanazawa University, Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa 920-8640, Japan. Ma Xiancai Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, Guangdong, China. Wang Zhe Department of Molecular Genetics, Kanazawa University, Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa 920-8640, Japan. 　/　Department of Medical Oncology, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China. 　/　The Key Laboratory of Biomarker High Throughput Screening and Target Translation of Breast and Gastrointestinal Tumor, Dalian University, Dalian 116001, China. Wakae, Kousho Department of Molecular Genetics, Kanazawa University, Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa 920-8640, Japan. Yuan Yaochang Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, Guangdong, China. He Zhangping Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, Guangdong, China. YOSHIYAMA, Hironori IIZASA, Hisashi Zhang Hui Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, Guangdong, China. Matsuda, Mami Department of Virology II, National Institute of Infectious Disease, Tokyo 164-8640, Japan. Sugiyama, Ryuichi Department of Virology II, National Institute of Infectious Disease, Tokyo 164-8640, Japan. Yuan Zhiyu College of Basic Medical Sciences, Shenyang Medical College, Shenyang 110034, China. Muramatsu, Masamichi Department of Molecular Genetics, Kanazawa University, Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa 920-8640, Japan muramatu@med.kanazawa-u.ac.jp muramatsu@nih.go.jp. Li Linghua Department of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou 510060, China llheliza@126.com.
Subject	interferon; hepatitis B virus (HBV; Hep B); microRNA (miRNA); p53; cytidine deaminase; RNA editing; ADAR1; cyclin G1; HBV; miR-122; p53
Journal Title	JOURNAL OF BIOLOGICAL CHEMISTRY
Volume	294
Issue	38
Start Page	14043
End Page	14054
ISSN	0021-9258
ISSN（Online）	1083-351X
Published Date	2019-09-20
DOI	10.1074/jbc.RA119.007970
PubMed ID	31366735
Publisher	AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
NII Type	Journal Article
OAI-PMH Set	Faculty of Medicine
Remark	This work was supported by National Natural Science Foundation of China Grant 81702856, Natural Science Foundation of Guangdong Province China Grant 2017A030310231, Liaoning Provincial Natural Science Foundation of China Grant 20180530041, and National Natural Science Foundation of China Grant 81501753, and the Research Program on Hepatitis from the Japan Agency for Medical Research and Development (AMED) Grant 18fk0310103j0302. The authors declare that they have no conflicts of interest with the contents of this article.