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language
eng
Attribute
Original Article
Author
Sutani, Akihisa
Description
Objective: In gastrointestinal endoscopy, the bleeding volume does not increase, even if a biopsy is performed under continuous warfarin administration. However, the safety when anticoagulant therapy is continued during flexible bronchoscopy has not been reported. We measured the actual blood loss in patients under continuous warfarin administration. Methods: This study was designed as a single-center, double-arm, prospective clinical trial. The bleeding volume during the procedure was calculated from aspirated secretions with a portable hemoglobin-measuring device. Results: Twenty-three subjects in the control group and 5 in the warfarin group were enrolled over a 60-month period. Overall, the blood loss in the warfarin group was comparable to that in the control group ( median 0.2 vs. 0.8 ml ) . No subject experienced severe blood loss. All patients in the warfarin group used a guide sheath. Conclusions: Although limited to peripheral lesions with a guide sheath, we found no severe bleeding in the warfarin group.
Subject
Flexible bronchoscopy
Warfarin
Bleeding
Blood loss
Journal Title
Shimane Journal of Medical Science
Volume
37
Issue
3
Start Page
95
End Page
101
ISSN
03865959
ISSN(Online)
24332410
Published Date
2020-09
NCID
AA00841586
DOI
DOI(SelfDOI)
Publisher
Faculty of Medicine, Shimane University
Publisher Aalternative
島根大学医学部
NII Type
Departmental Bulletin Paper
Format
PDF
Rights
Faculty of Medicine, Shimane University
Text Version
出版社版
OAI-PMH Set
Faculty of Medicine
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