Generation of interspecies limited chimeric nephrons using a conditional nephron progenitor cell replacement system

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Author	Yamanaka S. Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, 1058461, Japan Tajiri S. Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, 1058461, Japan Division of Regenerative Medicine, Jikei University School of Medicine, Tokyo, 1058461, Japan Fujimoto T. Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, 1058461, Japan Division of Regenerative Medicine, Jikei University School of Medicine, Tokyo, 1058461, Japan Matsumoto K. Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, 1058461, Japan Fukunaga S. Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, 1058461, Japan Department of Internal Medicine IV, Shimane University, Izumo, Shimane, 6938501, Japan Kim B. S. Division of Regenerative Medicine, Jikei University School of Medicine, Tokyo, 1058461, Japan Department of Urology, Kyungpook National University School of Medicine, Daegu, 41944, Korea Okano H. J. Division of Regenerative Medicine, Jikei University School of Medicine, Tokyo, 1058461, Japan Yokoo T. Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, 1058461, Japan
Journal Title	NATURE COMMUNICATIONS
Volume	8
ISSN	2041-1723
Published Date	2017-11-23
DOI	10.1038/s41467-017-01922-5
PubMed ID	29170512
Publisher	NATURE PUBLISHING GROUP
NII Type	Journal Article
OAI-PMH Set	Faculty of Medicine
Remark	We thank E. Kikuchi, H. Gotoh, and M. Ishida for experimental/technical assistance. Six2-Cre mice were gifted from Dr R. Nishinakamura (The Kumamoto University; Institute of Molecular Embryology and Genetics). This work was supported by grants from Japan Agency for Medical Research and Development (AMED) Grant Number 17ek0310006h0002 and Japan Society for the Promotion of Science (JSPS) KAKENHI Grant Number 17K16102, 16H03175. This work also was supported technically by The Jikei University School of Medicine.