Efficient inhibition of tumor angiogenesis and growth by a synthetic peptide blocking S100A4-methionine aminopeptidase 2 interaction

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Use this link to cite this item : https://ir.lib.shimane-u.ac.jp/53694

language	eng
Author	Ochiya Takahiro Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo, Japan Takenaga, Keizo Asagiri Masataka Nakano Kazumi The Institute of Medical Science, The University of Tokyo, Tokyo, Japan Satoh Hitoshi Department of Medical Genome Sciences, Laboratory of Tumor Cell Biology, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan Watanabe Toshiki Department of Medical Genome Sciences, Laboratory of Tumor Cell Biology, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan Imajoh-Ohmi Shinobu The Institute of Medical Science, The University of Tokyo, Tokyo, Japan Endo Hideya The Institute of Medical Science, The University of Tokyo, Tokyo, Japan / Department of Medical Genome Sciences, Laboratory of Tumor Cell Biology, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan
Journal Title	MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT
Volume	2
ISSN（Online）	2329-0501
Published Date	2015
DOI	10.1038/mtm.2015.8
PubMed ID	26029719
Publisher	CELL PRESS
NII Type	Journal Article
OAI-PMH Set	Faculty of Medicine
Remark	We thank S Mori, Emeritus Professor, and J Inoue, of the Institute of Medical Science, the University of Tokyo, for the initiation of the project and helpful discussion. We also thank Mariko Shimamura for her helpful assistance on in vivo angiogenesis assay. This work was supported in part by a Grant-in-Aid for the Third-Term Comprehensive 10-Year Strategy for Cancer Control, a Grant-in-Aid for Scientific Research on Priority Areas Cancer from the Ministry of Education, Culture, Sports, Science, and Technology, and the Program for Promotion of Fundamental Studies in Health Sciences of the National Institute of Biomedical Innovation (NiBio). This work was also supported by a Grant-in-Aid from the Japan Arteriosclerosis Research Foundation. Conceived and designed the experiments: H.E. Performed the experiments: T.O., K.T., M.A., S.I.-O., K.N., H.S., and H.E. Analyzed the data: T.O., K.T., and H.E. Wrote the paper: K.T., H.E., and T.O.