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File
language
eng
Attribute
original article
Author
Yamaguchi, Natsu
Tanabe, Tsuyoshi
Oshiro, Hitoshi
Nakabayashi, Narue
Fujita, Yasuyuki
Description
To identify pancreatic cancer’s etiology and to better understand its pathogenesis, we assessed the association between pancreatic and other cancers by determining the standardized mortality ratios (SMRs). We calculated sex-specific and partial correlations (adjusting for lung cancer SMR) between pancreatic and other cancers in 47 Japanese prefectures. Comparing the results for the decades 1998-2007, 1988-1997, and 1978-1987 revealed that pancreatic cancer’s SMR associates with those of lung, laryngeal, and bladder cancer in males, and stomach, colon, and rectal cancer in both sexes, and with ovarian cancer. The association with lung, laryngeal, and bladder cancer in males implicates tobacco smoking as a risk factor. The association with stomach cancer implies that Helicobacter pylori is a common risk factor. The association with colorectal cancer likely indicates that common factors such as obesity and high dietary fat may play etiological role. These results provide the clue to clarify the etiology of pancreatic cancer.
Journal Title
Shimane journal of medical science
Volume
28
Issue
1
Start Page
7
End Page
13
ISSN
03865959
ISSN(Online)
24332410
Published Date
2011-12-01
NCID
AA00841586
Publisher Aalternative
Shimane University Faculty of Medicine
NII Type
Departmental Bulletin Paper
Format
PDF
Text Version
出版社版
OAI-PMH Set
Faculty of Medicine
Remark
http://ci.nii.ac.jp/vol_issue/nels/AA00841586_jp.html
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