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Title Transcription
ギョルイ コクショク ソホウ ニタイスル ドパミン ノ メラノソーム ギョウシュウ サヨウ
Title Alternative (English)
Melanosome Aggregating Action of Dopamine on Fish Melanophores
File
language
eng
Author
Iga, Tetsuro
Description
The mechanism of melanosome-aggregating action of dopamine on fish melanophores was investigated, using isolated scales of Oryzias latipes. Dibenamine blocked the melanosome aggregation response of the melanophores to norepinephrine and to dopamine. Haloperidol inhibited the response to dopamine in both the innervated and denervated melanophores . The inhibition was pronounced in the denervated melanophores. Haloperidol accelerated the melanosome aggregating action of norepinephrine in the innervated melanophores, whereas in the denervated ones the drug inhibited the norepinephrine action . From these results, the following conclusions were suggested : The melanosome aggregation response induced by dopamine is not mediated through dopamine-specific receptors, but through alpha adrenergic receptors on the melanophores . Dopamire may act on the presynaptic endings to induce the release of the transmitter. Haloperidol also interacts with alpha adrenergic receptors of the melanophores.
Journal Title
Memoirs of the Faculty of Science, Shimane University
Volume
14
Start Page
95
End Page
101
ISSN
03879925
Published Date
1980-12-20
NCID
AN00108106
Publisher
島根大学理学部
Publisher Aalternative
The Faculty of Science, Shimane University
NII Type
Departmental Bulletin Paper
OAI-PMH Set
Faculty of Science and Engineering
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