Fibroblast Growth Factor-2 facilitates the growth and chemoresistance of leukemia cells in the bone marrow by modulating osteoblast functions

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Author	Sugimoto Keiki Fujii Memorial Research Institute, Otsuka Pharmaceutical Co. Ltd., Otsu, Shiga, Japan Miyata Yasuhiko Departments of Hematology, Nagoya Medical Center, Nagoya, Aichi, Japan Nakayama Takayuki Department of Transfusion Medicine, Aichi Medical University, Nagakute, Aichi, Japan Saito Shigeki Departments of Hematology, Japanese Red Cross Nagoya Daiini Hospital, Nagoya, Aichi, Japan SUZUKI, Ritsuro Hayakawa Fumihiko Departments of Hematology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan Nishiwaki Satoshi Depertment of Hematology and Oncology, Toyohashi Municipal Hospital, Toyohashi, Aichi, Japan Mizuno Hiroki Laboratory of Cellular Dynamics, World Premier International Research Center Initiative-Immunology Frontier Research Center, Osaka University, Suita, Japan Takeshita Kyosuke Departments of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan Kato Hidefumi Department of Transfusion Medicine, Aichi Medical University, Nagakute, Aichi, Japan Ueda Ryuzo Department of Tumor Immunology, Aichi Medical University, Nagakute, Aichi, Japan Takami Akiyoshi Department of Hematology, Aichi Medical University, Nagakute, Aichi, Japan Naoe Tomoki Departments of Hematology, Nagoya Medical Center, Nagoya, Aichi, Japan
Journal Title	SCIENTIFIC REPORTS
Volume	6
ISSN	2045-2322
Published Date	2016-08-2
DOI	10.1038/srep30779
PubMed ID	27481339
Publisher	NATURE PUBLISHING GROUP
NII Type	Journal Article
OAI-PMH Set	Faculty of Medicine
Remark	The authors wish to thank Ms. Yukiji Ando and Ms. Rie Goto for their contributions to various aspects of this work. This study was supported in part by a Japanese Grant-in-Aid for Scientific Research [(C) 20591118], a grant from the Japan Leukemia Research Fund and a grant from the Aichi Health Promotion Foundation to T. Nakayama.