Possible mechanism of hypothermia induced bu serum of a hypothermic patient in restrained rats

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m003002201002.pdf 128 KB エンバーゴ : 2006-04-16
タイトル
Possible mechanism of hypothermia induced bu serum of a hypothermic patient in restrained rats
著者
Sugimoto Naotoshi
Asai Akira
丸山 めぐみ
Koizumi Shoichi
収録物名
Shimane journal of medical science
22
1
開始ページ 7
終了ページ 11
収録物識別子
ISSN 03865959
EISSN 24332410
内容記述
その他
We experienced a patient who suffered from severe hypothermia. The etiology and mechanism of hypothermia were not known. Intraperitoneal (i.p.) injections of the patient's serum into restrained rats produced a significant hypothermia without associated changes in tail skin temperature. Heat balance of rats was then measured with direct and indirect calorimetry before and during the i.p. injection of the patient serum. The hypothermia induced by the patient's serum was associated with a reduction of oxygen consumption, but was not accompanied by changes in evaporative and nonevaporative heat loss. The results suggest that cryogenic substance(s), which was excessively produced in patient's blood, may affect thermogenic function and then produce hypothermia in rats.
言語
英語
資源タイプ 紀要論文
出版者
Shimane University Faculty of Medicine
発行日 2005-03-01
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
関連情報
[NCID] AA00841586
備考 http://ci.nii.ac.jp/vol_issue/nels/AA00841586_jp.html