Short-term and Long-term Outcomes of 13 Cases of Low-grade Appendiceal Mucinous Neoplasm （LAMN）

Abstract

Aim: We evaluated the outcomes and treatment strategy for low-grade appendiceal mucinous neoplasm （LAMN） cases at our institution. Methods: We conducted a clinicopathological assessment of LAMN resection cases performed within the Department of Gastroenterology and General Surgery at Shimane University Hospital from July 2013 to December 2022. This retrospective study utilized medical information from medical records, including age, gender, surgical procedures, pathology results, and postoperative courses. Results: There were 8 males and 5 females, and the mean age was 67.4 years. Two cases were preoperatively diagnosed as appendicitis, and 11 cases were preoperatively diagnosed as appendiceal tumor. Laparoscopic appendectomy was performed in 5 cases, laparoscopic partial cecal resection in 4 cases, and laparoscopic ileocecal resection with lymph node dissection was performed in 4 cases. All resection margins were negative and there were no lymph node metastases. No additional treatment was given for appendectomy cases, and all cases were recurrence-free （median follow-up: 27 months ［4–75 months］）. Conclusion: If the distance between the resection margins is sufficient, the postoperative follow-up period may be extended.