| ファイル情報(添付) |
Difference in P57 Expression Among Four Histological Types of Epithelial Ovarian Carcinoma.
1.26 MB
エンバーゴ :
2022-05-30
|
| タイトル |
Difference in P57 Expression Among Four Histological Types of Epithelial Ovarian Carcinoma.
|
| 著者 |
江角 知香
|
| 収録物名 |
Shimane Journal of Medical Science
|
| 巻 | 39 |
| 号 | 1 |
| 開始ページ | 33 |
| 終了ページ | 39 |
| 収録物識別子 |
ISSN 03865959
EISSN 24332410
|
| 内容記述 |
その他
P57 is known to have anti-tumor activity through inhibition of cyclin-dependent kinases. We performed immunohistochemical analysis on expression of P57 in 92 cases of epithelial ovarian carcinoma (EOC), of which, 31, 14, 18 and 29 were diagnosed as serous, mucinous, endometrioid (EC) and clear cell carcinoma (CCC), respectively. Of 92 cases of EOC, 6 and 28 were positive for P57 in the nucleus and the cytoplasm, respectively. Five cases of 29 CCC (17.2%) were positive in the nucleus, which was significantly greater than in non-CCC (p = 0.03). In contrast, positive cases in the cytoplasm were significantly greater in EC (55.6 and 23.0% for EC and non-EC, respectively, p = 0.01). Expression patterns of nuclear and cytoplasmic p57 showed no correlations with clinical stage of EOC. Clinicopathological significance of P57 expression in EOC would need further investigation.
|
| 主題 | |
| 言語 |
英語
|
| 資源タイプ | 紀要論文 |
| 出版者 |
Faculty of Medicine, Shimane University
島根大学医学部
|
| 発行日 | 2022-03 |
| 権利情報 |
Faculty of Medicine, Shimane University
|
| 権利関係（リンク） |  This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. |
| 出版タイプ | Version of Record（出版社版。早期公開を含む） |
| アクセス権 | オープンアクセス |
| 関連情報 |
[NCID] AA00841586
[DOI] 10.51010/sjms.39.1_33
|
