Transmitochondrial mice as models for primary prevention of diseases caused by mutation in the tRNA(Lys) gene

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Volume 111 Issue 8 Page 3104-3109 published_at 2014-02-25
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Title
Transmitochondrial mice as models for primary prevention of diseases caused by mutation in the tRNA(Lys) gene
Creator
Shimizu Akinori
Mito Takayuki
Hayashi Chisato
Ogasawara Emi
Koba Ryusuke
Negishi Issei
Nakada Kazuto
Hayashi Jun-Ichi
Source Title
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 111
Issue 8
Start Page 3104
End Page 3109
Journal Identifire
ISSN 0027-8424
Subjects
mutated mtDNA segregation; mtDNA heteroplasmic mutation; preimplantation genetic diagnosis; selection of oocytes ( Other)
Language
eng
Resource Type journal article
Publisher
NATL ACAD SCIENCES
Date of Issued 2014-02-25
Access Rights metadata only access
Relation
[DOI] 10.1073/pnas.1318109111
[PMID] 24510903
Remark This work was supported by Grants-in-Aid for Scientific Research A 25250011 (to J.-I.H.), Scientific Research A 23240058 (to K.N.), and Scientific Research on Innovative Areas 24117503 (to J.-I.H.) from the Japan Society for the Promotion of Science. This work was supported also by the World Premier International Research Center Initiative, Ministry of Education, Culture, Sports, Science and Technology-Japan (K.N. and J.-I.H.).