タイトル |
Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index
|
著者 |
Wen Wanqing
Zheng Wei
Okada Yukinori
Takeuchi Fumihiko
Tabara Yasuharu
Hwang Joo-Yeon
Dorajoo Rajkumar
Li Huaixing
Tsai Fuu-Jen
Yang Xiaobo
He Jiang
Wu Ying
He Meian
Zhang Yi
Liang Jun
Guo Xiuqing
Sheu Wayne Huey-Herng
Delahanty Ryan
Guo Xingyi
Kubo Michiaki
Yamamoto Ken
Ohkubo Takayoshi
Go Min Jin
Liu Jian Jun
Gan Wei
Chen Ching-Chu
Gao Yong
Li Shengxu
Lee Nanette R.
Wu Chen
Zhou Xueya
Song Huaidong
Yao Jie
Lee I-Te
Long Jirong
Tsunoda Tatsuhiko
Akiyama Koichi
Takashima Naoyuki
Cho Yoon Shin
Ong Rick T. H.
Lu Ling
Chen Chien-Hsiun
Tan Aihua
Rice Treva K.
Adair Linda S.
Gui Lixuan
Allison Matthew
Lee Wen-Jane
Cai Qiuyin
Umemura Satoshi
Kim Young Jin
Seielstad Mark
Hixson James
Xiang Yong-Bing
Isono Masato
Kim Bong-Jo
Sim Xueling
Lu Wei
Lee Juyoung
Lim Wei-Yen
Gao Yu-Tang
Takayanagi Ryoichi
Kang Dae-Hee
Wong Tien Yin
Hsiung ChaoAgnes
Wu I-Chien
Juang Jyh-Ming Jimmy
Shi Jiajun
Choi Bo Youl
Aung Tin
Hu Frank
Kim Mi Kyung
Lim WeiYen
Wang Tzung-Dao
Shin Min-Ho
Lee Jeannette
Ji Bu-Tian
Lee Young-Hoon
Young Terri L.
Shin Dong Hoon
Chun Byung-Yeol
Cho Myeong-Chan
Han Bok-Ghee
Hwu Chii-Min
Assimes Themistocles L.
Absher Devin
Yan Xiaofei
Kim Eric
Kuo Jane Z.
Kwon Soonil
Taylor Kent D.
Chen Yii-Der I.
Rotter Jerome I.
Qi Lu
Zhu Dingliang
Wu Tangchun
Mohlke Karen L.
Gu Dongfeng
Mo Zengnan
Wu Jer-Yuarn
Lin Xu
Miki Tetsuro
Tai E. Shyong
Lee Jong-Young
Kato Norihiro
Shu Xiao-Ou
Tanaka Toshihiro
|
収録物名 |
HUMAN MOLECULAR GENETICS
|
巻 | 23 |
号 | 20 |
開始ページ | 5492 |
終了ページ | 5504 |
収録物識別子 |
ISSN 0964-6906
EISSN 1460-2083
|
言語 |
英語
|
資源タイプ | 学術雑誌論文 |
出版者 |
OXFORD UNIV PRESS
|
発行日 | 2014-10-15 |
アクセス権 | メタデータのみ |
関連情報 |
[DOI] 10.1093/hmg/ddu248
[PMID] 24861553
|
備考 | This work was supported by the sources listed below. The funding information provided below pertains to the participating studies that contributed summary statistics to this meta-analysis. The funders of the original studies had no role in study design, data collection and analysis, decision to publish or preparation of this manuscript. The SGWAS was supported in part by US National Institutes of Health grants R37CA070867 (to W.Z.), R01CA082729 (to X.-O. S.), R01CA124558 (to W.Z.), R01CA148667 (to W.Z.) and R01CA122364 (G.Y.), as well as Ingram Professorship and Research Reward funds from the Vanderbilt University School of Medicine. Participating studies (grant support) in the Shanghai Genome-Wide Association Studies (SGWAS) are as follows: Shanghai Women's Health Study (R37CA070867 to W.Z.), Shanghai Men's Health Study (R01CA082729 to X.-O.S.), Shanghai Breast Cancer Study (R01CA064277 to X.-O.S.) and Shanghai Endometrial Cancer Study (R01CA092585 to X.-O.S.). We thank Regina Courtney for DNA preparation and Jing He for data processing and analyses. The JMGP was supported by Grants for Scientific Research (Priority Areas Medical Genome Science (Millennium Genome Project) and Applied Genomics, Leading Project for Personalized Medicine, and Scientific Research 20390185, 21390099, 19659163, 16790336, 12204008, 15790293, 16590433, 17790381, 17790381, 18390192, 18590265, 18590587, 18590811, 19590929, 19650188, 19790423, 17390186, 20390184 and 21390223) from the Ministry of Education, Culture, Sports, Science, and Technology, Japan; a Grants-in-Aid [H15-Longevity005, H17-longevity-003, H16-kenko-001, H18-longevity (kokusai), H11-longevity-020, H17-Kenkou-007, H17-pharmaco-common003, H18-Junkankitou (Seishuu)-Ippan-012 and H20-Junkankitou (Seishuu)-Ippan-009, 013] from the Ministry of Health, Labor and Welfare, Health and Labor Sciences Research Grants, Japan; a Science and Technology Incubation Program in Advanced Regions, Japan Science and Technology Agency; a Grants-in-Aid from the Japan Society for the Promotion of Science (JSPS) fellows (16.54041, 18.54042, 19.7152, 20.7198, 20.7477 and 20.54043), Tokyo, Japan; Health Science Research Grants and Medical Technology Evaluation Research Grants from the Ministry of Health, Labor and Welfare, Japan; the Japan Atherosclerosis Prevention Fund; the Uehara Memorial Foundation; the Takeda Medical Research Foundation; and the Japan Research Foundation for Clinical Pharmacology. The KARE project was supported by a grant from the Korea Center for Disease Control and Prevention (4845-301, 4851-302, 4851-307), and intramural grant from the Korea National Institute of Health (2012-N73002-00). The 5P2 and SiMES were supported by the Singapore Ministry of Health's National Medical Research Council under its Individual Research Grant funding scheme, the Singapore National Research Foundation under its Clinician Scientist Award and Singapore Translational Research Investigator Award funding schemes, which are administered by the Singapore Ministry of Health's National Medical Research Council and the Singapore Biomedical Research Council (BMRC) individual research grant funding scheme. The NHAPC study is supported by research grants including the National High Technology Research and Development Program (2009AA022704), Knowledge Innovation Program (KSCX2-EW-R-10), the National Natural Science Foundation of China (30930081, 81021002, 81170734) and the National Key Basic Research Program of China (2012CB524900).; GenSalt is supported by research grants (U01HL072507, R01HL087263 and R01HL090682) from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD. The CLHNS was supported by National Institutes of Health grants DK078150, TW05596, HL085144 and TW008288 and pilot funds from RR20649, E510126 and DK56350. We thank the Office of Population Studies Foundation research and data collection teams for the Cebu Longitudinal Health and Nutrition Survey. The CRC was supported by grants from the National Heart, Lung, and Blood Institute (HL071981), the National Institute of Diabetes and Digestive and Kidney Diseases (DK091718 and DK078616), the Boston Obesity Nutrition Research Center (DK46200) and United States Israel Binational Science Foundation Grant 2011036. The MESA and MESA SHARe project are conducted and supported by contracts N01-HC-95159 through N01-HC-95169 and RR-024156 from the National Heart, Lung, and Blood Institute (NHLBI). Funding for MESA SHARe genotyping was provided by NHLBI Contract N02-HL-6-4278. The authors thank the participants of the MESA study, the Coordinating Center, MESA investigators and study staff for their valuable contributions. A full list of participating MESA investigators and institutions can be found at http://www. mesa-nhlbi.org. The TAICHI Metabochip study was supported by NHLBI grant HL087647. Financial support for HALST was through grants from the National Health Research Institutes (PH-100-SP-01). The SAPPHERe was supported by grants from the National Health Research Institutes (BS-094-PP-01 & PH-100-PP-03). The TCAGEN was partially supported by grants NTUH.98-N1266, NTUH100-N1775, NTUH101-N2010, NTUH101-N, VN101-04 and NTUH 101-S1784 from National Taiwan University Hospital, NSC 96-2314-B-002-152 and NSC 101-2325-002-078. The TACT was supported by grants from the National Science Council of Taiwan (NSC96-2314-B-002-151, NSC-982314-B-002-122-MY2 and NSC 100-2314-B-002-115). The Taiwan Dragon and TACD were supported by grants from the National Science Council (NSC 98-2314-B-075A-002-MY3) and Taichung Veterans General Hospital, Taichung, Taiwan (TCVGH-1013001 C; TCVGH-1013002D). The Taiwan Genome Wide Association Study was supported by the Academia Sinica Genomic Medicine Multicenter Study (Academia Sinica 40-05-GMM) and Search and build the biosignatures for type 2 diabetes complications in the Han Chinese population (Academia Sinica 23-2 h), Academia Sinica, Taiwan, and the National Center for Genome Medicine at Academia Sinica (NC GM, NSC-101-2319-B-001-001) of the National Core Facility Program for Biotechnology (NCFPB) and the Translational Resource Center for Genomic Medicine (TRC, NSC-101-2325-B-001-035) of the National Research Program for Biopharmaceuticals (NRPB), National Science Council, Taiwan. |