Efficient inhibition of tumor angiogenesis and growth by a synthetic peptide blocking S100A4-methionine aminopeptidase 2 interaction

MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT Volume 2 published_at 2015
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Title
Efficient inhibition of tumor angiogenesis and growth by a synthetic peptide blocking S100A4-methionine aminopeptidase 2 interaction
Creator
Ochiya Takahiro
Asagiri Masataka
Nakano Kazumi
Satoh Hitoshi
Watanabe Toshiki
Imajoh-Ohmi Shinobu
Endo Hideya
Source Title
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT
Volume 2
Journal Identifire
EISSN 2329-0501
Language
eng
Resource Type journal article
Publisher
CELL PRESS
Date of Issued 2015
Access Rights metadata only access
Relation
[DOI] 10.1038/mtm.2015.8
[PMID] 26029719
Remark We thank S Mori, Emeritus Professor, and J Inoue, of the Institute of Medical Science, the University of Tokyo, for the initiation of the project and helpful discussion. We also thank Mariko Shimamura for her helpful assistance on in vivo angiogenesis assay. This work was supported in part by a Grant-in-Aid for the Third-Term Comprehensive 10-Year Strategy for Cancer Control, a Grant-in-Aid for Scientific Research on Priority Areas Cancer from the Ministry of Education, Culture, Sports, Science, and Technology, and the Program for Promotion of Fundamental Studies in Health Sciences of the National Institute of Biomedical Innovation (NiBio). This work was also supported by a Grant-in-Aid from the Japan Arteriosclerosis Research Foundation. Conceived and designed the experiments: H.E. Performed the experiments: T.O., K.T., M.A., S.I.-O., K.N., H.S., and H.E. Analyzed the data: T.O., K.T., and H.E. Wrote the paper: K.T., H.E., and T.O.