The antioxidant N-acetyl cysteine suppresses lidocaine-induced intracellular reactive oxygen species production and cell death in neuronal SH-SY5Y cells

BMC ANESTHESIOLOGY Volume 16 published_at 2016-10-24
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Title
The antioxidant N-acetyl cysteine suppresses lidocaine-induced intracellular reactive oxygen species production and cell death in neuronal SH-SY5Y cells
Creator
Okamoto Akihisa
Tanaka Masahiro
Sumi Chisato
Oku Kanako
Kusunoki Munenori
Nishi Kenichiro
Matsuo Yoshiyuki
Shingu Koh
Hirota Kiichi
Source Title
BMC ANESTHESIOLOGY
Volume 16
Journal Identifire
ISSN 1471-2253
Subjects
Lidocaine; Mitochondria; ROS; Redox; Apoptosis; Necrosis; Oxygen consumption ( Other)
Language
eng
Resource Type journal article
Publisher
BIOMED CENTRAL LTD
Date of Issued 2016-10-24
Access Rights metadata only access
Relation
[DOI] 10.1186/s12871-016-0273-3
[PMID] 27776485
Remark This work was supported by grants from the Japan Society for the Promotion of Science (KAKENHI; Grant #26670693 and #24592336 to K.H., and #25462457 to K.N.) and by the research grant D2 from Kansai Medical University.