Evaluation of the heterogeneous tissue distribution of erlotinib in lung cancer using matrix-assisted laser desorption ionization mass spectrometry imaging

SCIENTIFIC REPORTS Volume 7 published_at 2017-10-3
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Title
Evaluation of the heterogeneous tissue distribution of erlotinib in lung cancer using matrix-assisted laser desorption ionization mass spectrometry imaging
Creator
Hayashi Mitsuhiro
Aikawa Hiroaki
Ohuchi Mayu
Tamura Kenji
Fujiwara Yasuhiro
Hamada Akinobu
Source Title
SCIENTIFIC REPORTS
Volume 7
Journal Identifire
ISSN 2045-2322
Language
eng
Resource Type journal article
Publisher
NATURE PUBLISHING GROUP
Date of Issued 2017-10-3
Access Rights metadata only access
Relation
[DOI] 10.1038/s41598-017-13025-8
[PMID] 28974758
Remark We thank all the people related to this study including patient and family. We also thank N. Ohtsuka, S. Ryu, T. Yoshino, Y. Murai, M. Mizui, M. Nishidate, and R. Matsukane for their help. This work was supported by grants from the Accelerating Regulatory Science Initiative, Ministry of Health, Labour and Welfare, Japan (Y.F.), the National Cancer Center Development Fund (26-A-20, A.H.), and in part the Project for Cancer Research And Therapeutic Evolution, Japan Agency for Medical Research and Development (16cm0106223h0001, M.H.).