Microbiota maintain colonic homeostasis by activating TLR2/MyD88/PI3K signaling in IL-10-producing regulatory B cells

JOURNAL OF CLINICAL INVESTIGATION 129 巻 9 号 3702-3716 頁 2019-09-3 発行
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タイトル
Microbiota maintain colonic homeostasis by activating TLR2/MyD88/PI3K signaling in IL-10-producing regulatory B cells
著者
Liu Bo
Herzog Jeremy W.
Eun Chang Soo
Fan Ting-Jia
Bulik-Sullivan Emily
Carroll Ian M.
Hansen Jonathan J.
Chen Liang
Wilson Justin E.
Fisher Nancy C.
Ting Jenny P. Y.
Nochi Tomonori
Wahl Angela
Garcia J. Victor
Karp Christopher L.
Sartor R. Balfour
収録物名
JOURNAL OF CLINICAL INVESTIGATION
129
9
開始ページ 3702
終了ページ 3716
収録物識別子
ISSN 0021-9738
EISSN 1558-8238
言語
英語
資源タイプ 学術雑誌論文
出版者
AMER SOC CLINICAL INVESTIGATION INC
発行日 2019-09-3
アクセス権 メタデータのみ
関連情報
[DOI] 10.1172/JCI93820
[PMID] 31211700
備考 These studies were supported by NIH grants P01 DK094779, R01 DK53347, P40 OD010995, and P30 DK34987 (to RBS); R01 CA156330 (to JPYT); R01 AI123010 (to AW); and R01 AI111899, AI140799, and MH108179 (to JVG); and by Crohn's and Colitis Foundation Microbiome Initiative and Gnotobiotic Facility grants (both to RBS) and Research Fellowship Award (to YM and AO).; JEW was supported by a postdoctoral fellowship from the American Cancer Society (PF-13-401-01-TBE). The UNC Flow Cytometry Core is supported in part by Cancer Center Core Support Grant P30 CA016086 to the UNC Lineberger Comprehensive Cancer Center. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. The views expressed herein do not necessarily represent the views of the Bill & Melinda Gates Foundation. The authors acknowledge the editorial assistance of Richard Youngblood of the UNC Translational and Clinical Sciences Institute.