| File | |
| Title |
Aerobic Oxidative Sulfenylation of Pyrazolones and Pyrazoles Catalyzed by Metal-Free Flavin–Iodine Catalysis
|
| Creator |
Tanimoto Kazumasa
Ohkado Ryoma
|
| Source Title |
The Journal of Organic Chemistry
|
| Volume | 84 |
| Issue | 22 |
| Start Page | 14980 |
| End Page | 14986 |
| Journal Identifire |
ISSN 0022-3263
EISSN 1520-6904
|
| Descriptions |
Two-component metal-free catalytic oxidative sulfenylation of pyrazolones with thiols has been achieved using the biomimetic flavin and iodine. The methodology is mild and eco-friendly, proceeds in the presence of air or molecular oxygen (1 atm) as the sole sacrificial reagent, and generates water as the only byproduct. The methodology was also extended to the sulfenylation of pyrazoles and electron-rich benzenes and afforded a series of thioethers in good yields.
|
| Language |
eng
|
| Resource Type | journal article |
| Publisher |
American Chemical Society
|
| Date of Issued | 2019-10-22 |
| Publish Type | Accepted Manuscript |
| Access Rights | open access |
| Relation |
[DOI] 10.1021/acs.joc.9b02422
[URI] https://pubs.acs.org/doi/abs/10.1021/acs.joc.9b02422
|
