Effect of Surgical Instruments on Cytological Features: A Pilot Study of Mouse Tongue Cancer Models

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ファイル情報(添付)
タイトル
Effect of Surgical Instruments on Cytological Features: A Pilot Study of Mouse Tongue Cancer Models
著者
絲原 千映子
収録物名
Shimane Journal of Medical Science
34
1
開始ページ 7
終了ページ 11
収録物識別子
ISSN 03865959
EISSN 24332410
内容記述
抄録・要旨
Rapid intraoperative cytology is a common method for examining resection margins in cancer surgery. Cytopathologists often face challenges with cytological diagnoses because of cell degeneration by electric scalpels. This pilot study sought to elucidate the effect of surgical instruments on cytological features.
Mouse models of tongue SCC were used (n = 10). Tumor was excised using a stainless-steel scalpel (n = 2, SS), electronic scalpel (n = 2, ES), or ultrasonic scalpel (n = 2, HS). Imprint cytology specimens from resected tumor were subjected to Papanicolaou (Pap) or Giemsa staining. Remaining tissue was stained with hematoxylin and eosin. In SS specimens, heat-induced cell degeneration was observed less extensively than in ES. In perioperative rapid intraoperative cytology examination, surgeons should consider the possibility of changes in cellular morphology depending on the type of surgical instrument used. The cytopathologist should also be informed about the instrument used to resect the specimens.
主題
surgical scalpel
oral cancer
rapid intraoperative cytology
cytopathy
言語
英語
資源タイプ 紀要論文
出版者
Faculty of Medicine, Shimane University
島根大学医学部
発行日 2017-07-31
権利情報
Faculty of Medicine, Shimane University
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
関連情報
[NCID] AA00841586