Bulletin of the Faculty of Life and Environmental Science Shimane University

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Bulletin of the Faculty of Life and Environmental Science Shimane University 1
1996-12-20 発行

インドヒラマキガイからの生理活性ペプチドの単離

Structure and actions of some neuropeptides isolated from the freshwater pulmonate, Indoplanorbis exustus
Fujimoto, Masaaki
Hayashi, Mika
Matsushima, Osamu
Muneoka, Yojiro
Minakata, Hiroyuki
Nomoto, Kyosuke
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Description
Eight bioactive peptides were purified from the pulmonate snail Indoplanorbis exustus using the isolated crop of another pulmonate snail, Euhadra congenita, as bioassay system. Amino acid sequences of these peptides were the same as or homologous to those of peptides so far reported, including FMRFamide, SCP and buccalin family peptides. All these peptides showed inhibitory effects on spontaneous contractions of the crop. It seems that GDPFLRFamide serves as a representative peptide of FMRFamidefamily in this species.