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language
eng
Author
Miyawaki Shingo Biomedical Animal Research Laboratory, Institute for Genetic Medicine, Hokkaido University, Hokkaido, 060-0815, Japan Department of Physiology, Keio University School of Medicine, Tokyo, 160-8582, Japan Division of Immunobiology, Institute for Genetic Medicine, Hokkaido University, Hokkaido, 060-0815, Japan
Kawamura Yoshimi Biomedical Animal Research Laboratory, Institute for Genetic Medicine, Hokkaido University, Hokkaido, 060-0815, Japan View author publications
Oiwa Yuki Biomedical Animal Research Laboratory, Institute for Genetic Medicine, Hokkaido University, Hokkaido, 060-0815, Japan Division of Immunobiology, Institute for Genetic Medicine, Hokkaido University, Hokkaido, 060-0815, Japan
Shimizu Atsushi Division of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, 028-3694, Japan
Hachiya Tsuyoshi Division of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Iwate, 028-3694, Japan
Bono Hidemasa Database Center for Life Science, Research Organization of Information and Systems, Mishima, 411-8540, Japan
Koya Ikuko Department of Physiology, Keio University School of Medicine, Tokyo, 160-8582, Japan
Okada Yohei Department of Physiology, Keio University School of Medicine, Tokyo, 160-8582, Japan Department of Neurology, Aichi Medical University School of Medicine, Aichi, 480-1195, Japan
Kimura Tokuhiro Department of Pathology, Yamaguchi University Graduate School of Medicine, Yamaguchi, 755-8505, Japan
Tsuchiya Yoshihiro Department of Pharmacology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, 142-8501, Japan
Suzuki Sadafumi Department of Physiology, Keio University School of Medicine, Tokyo, 160-8582, Japan
Onishi Nobuyuki Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, 160-8582, Japan
Kuzumaki Naoko Department of Physiology, Keio University School of Medicine, Tokyo, 160-8582, Japan Department of Pharmacology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, 142-8501, Japan
Narita Minoru Department of Pharmacology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, 142-8501, Japan
Ikeda Eiji Department of Pathology, Yamaguchi University Graduate School of Medicine, Yamaguchi, 755-8505, Japan
Okanoya Kazuo Graduate School of Arts and Science, The University of Tokyo, Tokyo, 153-8902, Japan
Seino Ken-ichiro Division of Immunobiology, Institute for Genetic Medicine, Hokkaido University, Hokkaido, 060-0815, Japan
Saya Hideyuki Division of Immunobiology, Institute for Genetic Medicine, Hokkaido University, Hokkaido, 060-0815, Japan
Okano Hideyuki Department of Physiology, Keio University School of Medicine, Tokyo, 160-8582, Japan
Miura Kyoko Biomedical Animal Research Laboratory, Institute for Genetic Medicine, Hokkaido University, Hokkaido, 060-0815, Japan Department of Physiology, Keio University School of Medicine, Tokyo, 160-8582, Japan PRESTO, Japan Science and Technology Agency, Saitama, 332-0012, Japan
Journal Title
NATURE COMMUNICATIONS
Volume
7
ISSN
2041-1723
Published Date
2016-05
DOI
PubMed ID
Publisher
NATURE PUBLISHING GROUP
NII Type
Journal Article
OAI-PMH Set
Faculty of Medicine
Remark
We thank Drs D. Sipp for proofreading the manuscript; J. Kohyama, A. Takaoka and professors at the Institute for Genetic Medicine Hokkaido University for their administrative support and scientific discussion; N. Arai, C. Fukaya, Y. Tanabe and Y. Fujimura for help with animal maintenance; S. Osuka and all members of the H.O. and K.M. laboratories for technical assistance and scientific discussion; S. Yamanaka, K. Okita and K. Takahashi for 20D17-, 38C2 Nanog-EGFP Ms-iPSCs and 201B7 human-iPSCs; K. Niibe for N3E6 Ms-iPSCs; M. Ikawa and M. Okabe for EGR-G101 ESCs; H. Miyoshi for lentiviral vectors; T. Kitamura for PLAT-E and pMXs retroviral vectors; J. Miyazaki for pCAGGS-hLIF vectors; H. Naka-Kaneda for pCSII-EF-RfA-TK-hyg vector. This work was supported in part by PRESTO of the Japan Science and Technology Agency to K. M.; Grants-in-Aid for Scientific Research from the Japanese Society for the Promotion of Science from the Ministry of Education, Culture, Sports, Science and Technology (MEXT) to K. M. and Y. K.; Grant-in-Aid for Scientific Research on Innovative Areas 'Oxygen Biology: a new criterion for integrated understanding of life' from the MEXT to K. M.; and the Funding Program for World-Leading Innovative R&D on Science and Technology (FIRST Program) to H.O. K. M. was supported by the Takeda Science Foundation, Mitsubishi Foundation, Japan Foundation For Aging And Health, Sekisui Chemical Innovations Inspired by Nature Research Support Program, Astellas Foundation for Research on Metabolic Disorders and Mochida Memorial Foundation for Medical and Pharmaceutical Research. K.M. and S.M. were Research Fellows of the Japanese Society for the Promotion of Science.
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