SWAN

One-year Ocular Safety Observation of Workers and Estimations of Microorganism Inactivation Efficacy in the Room Irradiated With 222-nm Far Ultraviolet-C Lamps

Creator	SUGIHARA Kazunobu
Journal	Photochemistry and photobiology Volume 99 Issue 3 pp. 967 - 974
Date of Issued	published_at 2025-03-05

Comparison of Oral Health-Related Quality of Life Among Endodontic Patients With Irreversible Pulpitis and Pulp Necrosis Using the Oral Health-Related Endodontic Patient's Quality of Life Scale

Creator	FADIL ABDILLAH ARIFIN
Journal	Odontology Volume 113 pp. 844 - 856
Date of Issued	published_at 2025-03-19

The Effect of Management of Older Patients With Heart Failure by General Physicians on Mortality and Hospitalization Rates: a Retrospective Cohort Study

Creator	Nishikawa Kasumi ( Abe, Kasumi )
Journal	BMC Primary Care Volume 25
Date of Issued	published_at 2025-03-19

UBE3A Controls Axon Initial Segment in the Cortical Pyramidal Neurons

Creator	LIU XINLANG
Journal	Biochemical and Biophysical Research Communications Volume 751
Date of Issued	published_at 2025-03-19

In Vivo Evaluation of Bone Regeneration Capacity of the Novel Nanobiomaterial: β-Tricalcium Phosphate Polylactic Acid-co-glycolide (β-TCP/PLLA/PGA) for Use in Maxillofacial Bone Defects

Creator	RAMANATHAN MRUNALINI
Journal	Nanomaterials Volume 14 Issue 1
Date of Issued	published_at 2025-03-19

Oral Functional Impairment May Cause Malnutrition Following Oral Cancer Treatment in a Single‑center Cross‑sectional Study

Creator	Morioka Reon
Journal	Scientific Reports Volume 12
Date of Issued	published_at 2025-03-19

Effects of Shopping Rehabilitation on Older People's Daily Activities

Creator	Mouri Naoto
Journal	International Journal of Environmental Research and Public Health Volume 19 Issue 1
Date of Issued	published_at 2025-03-19

Comparison of Schlemm’s Canal Morphology Parameters Between Propensity Score Matched Primary Open-Angle Glaucoma and Exfoliation Glaucoma

Creator	Tsutsui Aika
Journal	Investigative Ophthalmology & Visual Science Volume 65 Issue 15
Date of Issued	published_at 2025-03-19

Clinical Characteristics of Japanese Patients With Corticobasal Degeneration

Creator	田原大資
Journal	Journal of the Neurological Sciences Volume 466
Date of Issued	published_at 2025-03-19

Impact of Current and Previous Sperm Findings on Outcomes of Intrauterine Insemination

Creator	Taniguchi Maki
Journal	Reproductive Medicine and Biology Volume 23 Issue 1
Date of Issued	published_at 2025-03-19

Association Between KRAS and PIK3CA Mutations and Progesterone Resistance in Endometriotic Epithelial Cell Line

Creator	Kanno Kosuke
Journal	Current issues in molecular biology Volume 46 Issue 4 pp. 3579 - 3594
Date of Issued	published_at 2025-03-19

Discrepancy Between Subjective and Objective Postoperative Oral Dysfunction Assessment After Oral Cancer Treatment: A Single-Center Cross-Sectional Study

Creator	Kato Akira
Journal	Oral oncology Volume 129
Date of Issued	published_at 2025-03-19

NAD⁺ Deficiency Plays Essential Roles in the Hyperuricemia of Stroke-Prone Spontaneously Hypertensive Rat via Xanthine Dehydrogenase to Xanthine Oxidase Conversion

Creator	AMELIA FERDAUS SARA
Journal	Biochemical and biophysical research communications Volume 744
Date of Issued	published_at 2025-03-19

Relationship Between Anemia and Readmission Among Older Patients in Rural Community Hospitals:A Retrospective Cohort Study

Creator	Amano Shiho
Journal	Journal of clinical medicine Volume 13 Issue 2 pp. 539 -
Date of Issued	published_at 2025-03-19

The PKM2 Activator TEPP-46 Suppresses Cellular Senescene in Hydrogen Peroxide-induced Proximal Tubular Cells and Kidney Fibrosis in CD-1 db/db Mice.

Creator	Ishihara Shin-Ichiro
Journal	Journal of diabetes investigation Volume 16 Issue 4 pp. 598 - 607
Date of Issued	published_at 2025-03-19

Persistent Epstein-Barr Virus Infection of Epithelial Cells Leads to APOBEC3C Expression and Induces Mitochondrial DNA Mutations

Creator	AUNG PHYO WAI
Journal	Microbiology and Immunology Volume 69 pp. 157 - 167
Date of Issued	published_at 2025-03-19

The Gut Microbiota Response to Electroconvulsive Therapy for Schizophrenia : A Prospective Cohort Study

Creator	KANAYAMA Misako
Journal	Shimane Journal of Medical Science Volume 41 pp. 83 - 91
Date of Issued	published_at 2025-03-19

A Diet High in Glucose and Deficient in Dietary Fibre Causes Fat Accumulation in the Liver without Weight Gain

Creator	Karino Sonoko
Journal	Biochemistry and Biophysics Reports Volume 40
Date of Issued	published_at 2025-03-05

A Genome-wide Association Study Identifies a Locus Associated With Knee Extension Strength in Older Japanese Individuals

Creator	Ito Shuji
Journal	Communications Biology Volume 7 Issue 513 (2024)
Date of Issued	published_at 2025-03-05

Investigating the Regulatory Mechanism of Glucose Metabolism by Ubiquitin-like Protein MNSFβ

Creator	Kono Megumi
Journal	Molecular biology reports Volume 51 Issue 1
Date of Issued	published_at 2025-02-10

Dietary Fiber Deficiency Accelerates Colitis in Mice in the Short Term Independent of Short-Chain Fatty Acids

Creator	KANDA Shoma
Journal	Gastroenterol. Insights Volume 15 Issue 3 pp. 730 - 743
Date of Issued	published_at 2024-12-04

Clinicopathological comparison between PTCL-TBX21 and PTCL-GATA3 in Japanese patients

Creator	SHIMASAKI Yasumasa
Journal	Cancer Medicine Volume 13 Issue 3
Date of Issued	published_at 2024-12-04

スベロイルアニリドヒドロキサム酸の抗EBV活性の探求：BART遺伝子発現の抑制と溶解感染の誘導による感染細胞のアポトーシス誘導

Creator	LIU YUXIN
Journal
Date of Issued	published_at 2024-09-20

Effect of Bone Density on the Drill-Hole Diameter Made by a Cannulated Drill Bit in Cancellous Bone

Creator	UTOMO ANDI PANGNGURISENG
Journal
Date of Issued	published_at 2024-09-20

インスリン様成長因子ｌ受容体シグナル伝達経路の遮断はA型ボツリヌス毒素療法後の神経筋接合部の再生を阻害する

Creator	ISHIHARA Hiroki
Journal
Date of Issued	published_at 2024-09-04

非外傷重症患者におけるハイブリッドERの有効利用

Creator	MATSUMOTO Ryo
Journal
Date of Issued	published_at 2024-04-03

長期療養高齢者の緩和ケア指針の開発

Creator	井上かおり
Journal
Date of Issued	published_at 2024-03-22

島根大学プロスタグランジン関連眼周囲症分類によるトラベクレクトミー成績比較

Creator	ISHIDA Akiko
Journal
Date of Issued	published_at 2024-03-22

高純度間葉系幹細胞RECからのミトコンドリア移入によりMELAS由来神経機能が回復する

Creator	LIU LU
Journal
Date of Issued	published_at 2024-03-22

日本の地方都市における2010年代後半の急性冠症候群の中期予後の検討

Creator	YASUDA Yu
Journal
Date of Issued	published_at 2024-03-22

ヒドロシキクロロキンはBcl-xL阻害により誘導されるBxPC-3ヒト膵がん細胞のアポトーシスを促進する

Creator	HOQUE MOHAMMAD MAHBUBUL
Journal
Date of Issued	published_at 2024-03-22

高脂肪食がSHR-SPラット脳の小血管病の病理変化に対する影響

Creator	ZHANG YUCHI
Journal
Date of Issued	published_at 2024-03-22

下垂体および視床下部における下垂体性腺刺激ホルモンの調節に対する性ステロイドの影響

Creator	SUSDIAMAN SUDIN YACCA
Journal
Date of Issued	published_at 2024-03-22

心血管疾患手術患者における口腔内細菌数と術後合併症との関係：後方視的コホート研究

Creator	OSAKO Rie
Journal
Date of Issued	published_at 2024-03-22

精神障害者のがん治療における格差の理由　がん医療従事者及び精神科医療従事者に対する質的調査

Creator	Eto Tsuyoshi
Journal
Date of Issued	published_at 2024-03-22

顎顔面骨手術における新規骨伝導性生体吸収性を有するu-HA/PLLA/PGAプレートの有用性に関する基礎的研究

Creator	ISHIZUKA Shinji
Journal
Date of Issued	published_at 2024-03-22

アーメド緑内障バルブの流圧特性とチューブ内に残存する空気の影響

Creator	ANDI MASDIPA
Journal
Date of Issued	published_at 2024-03-22

高アンドロゲン状態は視床下部KNDyニューロンにおけるKiss-1,Tac2,DynA発現の比例した変化を生じる

Creator	OKADA Hiroe
Journal
Date of Issued	published_at 2024-03-15

軽度認知障害におけるフィードバック関連陰性電位の検討

Creator	ABE Satoshi
Journal
Date of Issued	published_at 2024-03-05

経皮的冠動脈形成術後の長期主要心血管イベントに対するアポリポ蛋白の予測的役割

Creator	KAWAHARA Hiroshi
Journal
Date of Issued	published_at 2024-02-07

ApoE遺伝子欠損は高血圧自然発症ラットにおいて動脈脂質沈着を促進させる

Creator	MATSUO Hiroyuki
Journal
Date of Issued	published_at 2023-10-04

外科切除肺の超拡大内視鏡像とH&E像との比較

Creator	KOBAYASHI Misato
Journal
Date of Issued	published_at 2023-12-25

インシリコ解析により，mir-6770-5pはすべてのB型肝炎ウイルス遺伝子型のX遺伝子を標的とすることが予測される

Creator	AMRIZAL MUCHTAR HADELE
Journal
Date of Issued	published_at 2023-10-04

ミスマッチ修復機能欠損のtype2子宮体癌における免疫チェックポイント阻害剤の有用性の検討

Creator	SAWADA Kiyoka
Journal
Date of Issued	published_at 2023-09-06

活性化型マウスIL-18のネオエピトープに対する拮抗性モノクローナル抗体の作製とその評価方法の開発

Creator	UCHIDA Yuki
Journal
Date of Issued	published_at 2023-09-06

外科的に切除された膵癌におけるST2発現の臨床病理学的及び予後との関連性の検討

Creator	NAGASE Mamiko
Journal
Date of Issued	published_at 2023-07-05

高純度間葉系幹細胞は機能的ミトコンドリア投入に優れている

Creator	YANG JIAHAO
Journal
Date of Issued	published_at 2023-06-29

チューブリンの翻訳後修飾の調節因子であるCCP1は，小脳の発達に重要な役割を果たす可能性があります。

Creator	PANG BO
Journal
Date of Issued	published_at 2023-06-29

開放隅角緑内障患者における落屑の有無によるAdvanced Glycation End Productの蓄積状況

Creator	Shirakami Tomoki
Journal
Date of Issued	published_at 2023-06-29

飲酒は，食塩摂取量が血圧とアルブミン尿に与える影響を増強する

Creator	YOSHIMURA Ryuichi
Journal
Date of Issued	published_at 2023-03-17

日本の非認知症母集団において脈圧は認知能力と関連している

Creator	水原亮
Journal
Date of Issued	published_at 2023-01-11

新たに開発された骨補填材３次元多孔質β-TCP/PDLLAの顎顔面骨への応用に関する検討

Creator	TODA Erina
Journal
Date of Issued	published_at 2023-03-17

新規開発した非焼成／未焼成ハイドロキシアパタイトと糖含有ポリ-L-乳酸シートの顎顔面外科手術における骨再生能に関するin vivo研究

Creator	NGO XUAN HUY
Journal
Date of Issued	published_at 2023-03-17

最終糖化産物（AGEs)スコアと糖尿病網膜症病期の関連

Creator	Takayanagi Yuji
Journal
Date of Issued	published_at 2023-03-17

マイクロサテライト不安定性の低い卵巣類内膜癌および明細胞癌（内膜関連癌）における免疫チェックポイント阻害剤および他の抗癌剤との併用療法の有益性について

Creator	Nonomura Yuki
Journal
Date of Issued	published_at 2023-03-17

下顎骨区域切除後の遊離腓骨皮弁による二次下顎再建の安全性と有効性に関する検討：後方視的症例対象研究

Creator	YAMAKAWA Sho
Journal
Date of Issued	published_at 2023-03-17

眼内レンズの前方移動に関わる力とそれを規定する因子の測定

Creator	MOCHIJI Mihoko
Journal
Date of Issued	published_at 2023-03-17

卵巣低異型度漿液性癌のin vitro発癌モデル

Creator	PUJA DEY
Journal
Date of Issued	published_at 2023-03-17

電気けいれん療法はリポポリサッカライド誘発ラットにおけるうつ様行動を改善する

Creator	SULTANA JANNATUL FERDOUSH JERIN
Journal
Date of Issued	published_at 2023-03-17

APPトランスジェニックマウス尿のiTRAQ法を用いたタンパク分析

Creator	ZHOU XIAOJING
Journal
Date of Issued	published_at 2023-03-17

アルツハイマー病モデルマウスにおける脳小血管変化の分析

Creator	SHIBLY ABU ZAFFAR
Journal
Date of Issued	published_at 2023-03-17

肺がん細胞の senolysis とferroptosis において細胞質 p21Cip1/Waf1 は防御的に作用する

Creator	KOYANAGI Akira
Journal
Date of Issued	published_at 2023-03-17

マイクロRNA miR-126-3p とmiR-199-3p はHIF-1αとC/EBPαの発現制御を介して3T3-L1細胞由来脂肪細胞内の脂肪蓄積を促進する。

Creator	ISRAT JAHAN
Journal
Date of Issued	published_at 2023-03-17

大腸がんの加齢マウスに対して化学免疫療法を実施した場合に誘導される抗がん効果に及ぼすL-Arginine補充の修飾効果

Creator	ISHITOBI Kazunari
Journal
Date of Issued	published_at 2023-03-17

一般住民における多疾患重積は脆弱性骨折のリスクである

Creator	A GARU
Journal
Date of Issued	published_at 2023-03-17

ブタを用いた体外循環における模型人工肺のガス交換性能および血液凝固に及ぼす低体温の影響

Creator	Akeho Kazuhiro
Journal
Date of Issued	published_at 2023-03-17

モルヒネ長期投与による体性・内臓刺激に対するレミフェンタニルの抗侵害受容作用への交叉耐性の検討

Creator	Mori Hideaki
Journal
Date of Issued	published_at 2023-03-17

MRI評価に基づく機械的血栓除去術後の頭蓋内高吸収領域に対するDECTの診断制度の検証

Creator	EDA Hirotake
Journal
Date of Issued	published_at 2023-03-17

頸動脈ステント留置術における解剖学的危険因子の影響に関する研究

Creator	KAMBARA Mizuki
Journal
Date of Issued	published_at 2023-3-3

卵巣漿液粘液性腫瘍の日本人における遺伝子変異の解析

Creator	SASAMORI Hiroki
Journal
Date of Issued	published_at 2023-3-15

日本における無症候性Galactose-α-1,3-galactose感作のコホート研究

Creator	NAKAGAWA Yusei
Journal
Date of Issued	published_at 2023-2-10

間葉系幹細胞の形態情報に基づく非侵襲的な継代能力の早期予測

Creator	Suyama Takashi
Journal
Date of Issued	published_at 2023-02-10

Combinational elastographyをもちいた肝線維化評価について

Creator	YAZAKI Tomotaka
Journal
Date of Issued	published_at 2022-12-7

海綿骨スクリューにおけるねじ山深さと固定強度の関係

Creator	YU AORIGELE
Journal
Date of Issued	published_at 2022-12-26

A mesenchymal stem cell line transplantation improves neurological function and angiogenesis in intraventricular amyloid β infusion rats

Creator	Md. Ahsanul Haque
Journal
Date of Issued	published_at 2018

Cotylenin A and tyrosine kinase inhibitors synergistically inhibit the growth of chronic myeloid leukemia cells

Creator	IKEJIRI Fumiyoshi
Journal
Date of Issued	published_at 2018

Nutritional Status is Associated With Non-Cardiovascular Mortality but not With Cardiovascular Mortality in Maintenance Hemodialysis Patients

Creator	MATAGA Kentaro
Journal
Date of Issued	published_at 2017

Prognostic Impact of B-Type Natriuretic Peptide in Elderly Patients With Severe Aortic Stenosis

Creator	Okada Taiji
Journal
Date of Issued	published_at 2018

RNAi‑dependent heterochromatin assembly in fission yeast Schizosaccharomyces pombe requires heat‑shock molecular chaperones Hsp90 and Mas5

Creator	Okazaki Kosuke
Journal
Date of Issued	published_at 2018-01-27

Performance evaluation of a direct-conversion flat-panel detector system in imaging and quality assurance for a high-dose-rate 192 Ir source

Creator	Miyahara Yoshinori
Journal
Date of Issued	published_at 2018-03-08

Optimal route of diphtheria toxin administration to eliminate native nephron progenitor cells in vivo for kidney regeneration

Creator	FUKUNAGA Shohei
Journal
Date of Issued	published_at 2018-01-31

Effect of Age on Effectiveness of Vonoprazan in Triple Therapy for Helicobacter pylori Eradication

Creator	Kusunoki Maho
Journal
Date of Issued	published_at 2019-6-1

Generation and characterization of antagonistic anti-human interleukin (IL)- 18 monoclonal antibodies with high affinity: Two types of monoclonal antibodies against full-length IL-18 and the neoepitope of inflammatory caspase-cleaved active IL-18

Creator	Nariai Yuko \| KAMINO Hiroki \| OBAYASHI Eiji \| Kato Hiroaki \| SAKASHITA Gyosuke \| Sugiura Tomoko \| Migita Kiyoshi \| Koga Tomohiro \| Kawakami Atsushi \| Sakamoto Kazuma \| Kadomatsu Kenji \| Nakakido Makoto \| Tsumoto Kouhei \| Urano Takeshi
Journal
Date of Issued	published_at 2019-01-04

Tropomyosin is a minor but distinct allergen in patients with shrimp allergies in Japan

Creator	Onon Tsedendorj \| CHINUKI Yuko \| UEDA Kiyoe \| KOHNO Kunie \| Adachi Atsuko \| Morita Eishin
Journal
Date of Issued	published_at 2018-04-30

How asymptomatic are early cancer patients of five organs based on registry data in Japan

Creator	NAKABAYASHI Narue
Journal
Date of Issued	published_at 2018-11-7

Capabilities of fecal calprotectin and blood biomarkers as surrogate endoscopic markers according to ulcerative colitis disease type

Creator	SONOYAMA Hiroki \| KAWASHIMA Kosaku \| ISHIHARA Shunji \| Kotani Satoshi \| Fukuba Nobuhiko \| Akihiko Oka \| Kusunoki Ryusaku \| Tada Yasumasa \| MISHIMA Yoshiyuki \| Ohshima Naoki \| MORIYAMA Ichiro \| Yuki Takafumi \| Onishi Koji \| Kinoshita Yoshikazu
Journal
Date of Issued	published_at 2019-3-6

Adding acotiamide to gastric acid inhibitors is effective for treating refractory symptoms in patients with non-erosive reflux disease

Creator	Yamashita Hiroshi \| Okada Akihiko \| Naora Kohji \| HONGO Masafumi \| Kinoshita Yoshikazu
Journal
Date of Issued	published_at 2019-03-22

Piperlongumine rapidly induces the death of human pancreatic cancer cells mainly through the induction of ferroptosis

Creator	Yamaguchi Yuki \| KASUKABE Takashi \| Kumakura Shiyunichi
Journal
Date of Issued	published_at 2019-03-22

Evaluation of Pathological Association between Stroke-related QTL and Salt-induced Renal Injury in Stroke-Prone Spontaneously Hypertensive Rat

Creator	Mohammad Farhadur Reza \| Davis Ngarashi \| Koike Masamichi \| Misumi Masaki \| OHARA Hiroki \| Nabika Toru
Journal
Date of Issued	published_at 2019-03-22

Carteolol hydrochloride reduces visible light-induced retinal damage in vivo and BSO/glutamate-induced oxidative stress in vitro

Creator	Masato Matsuo \| Kuse Yoshiki \| Takahashi Kei \| Kuwahara Keiichi \| Tanito Masaki \| KAIZU Sachiko \| Shimazawa Masamitsu \| Hara Hideaki \| Ohira Akihiro
Journal
Date of Issued	published_at 2019-03-22

Circumferential distribution and clinical characteristics of esophageal cancer in lower esophagus – differences related to histological subtype

Creator	OKADA Mayumi \| Ishimura Norihisa \| MIKAMI Hironobu \| OKIMOTO Eiko \| Ohshima Naoki \| Miyaoka Youichi \| Fujishiro Hirofumi \| Ishihara Shunji \| Kinoshita Yoshikazu
Journal
Date of Issued	published_at 2019-03-22

Dual inhibition of NADPH oxidases and xanthine oxidase potently prevents salt-induced stroke in stroke-prone spontaneously hypertensive rats

Creator	Ngarashi Davis \| フジカワコウイチ \| Ferdaus Mohammed \| Zahid Hasan \| OHARA Hiroki \| Nabika Toru
Journal
Date of Issued	published_at 2019-03-22

Bullous Pemphigoid IgG Induces Cell Dysfunction and Enhances the Motility of Epidermal Keratinocytes via Rac1/Proteasome Activation

Creator	Duerna Tie \| Xia Da \| Natsuga Ken \| Yamamoto Osamu \| Morita Eishin
Journal
Date of Issued	published_at 2019-03-22

Serotonin-1A receptor C-1019G polymorphism affects brain functional networks

Creator	ZHENG HAIXIA \| Onoda Keiichi \| WADA Yasuko \| MITAKI Shingo \| Nabika Toru \| Yamaguchi Shuhei
Journal
Date of Issued	published_at 2019-03-22

Effects of the Prdx2 depletion on blood pressure and life span in spontaneously hypertensive rats.

Creator	Mahal Zinat \| フジカワコウイチ \| MATSUO Hiroyuki \| Zahid Hasan \| Koike Masamichi \| Misumi Masaki \| Kaneko Takehito \| Mashimo Tomoji \| OHARA Hiroki \| Nabika Toru
Journal
Date of Issued	published_at 2019-03-22

ARID1B as a Potential Therapeutic Target for ARID1A-Mutant Ovarian Clear Cell Carcinoma

Creator	Sato Emi \| NAKAYAMA Kentaro \| Sultana Razia \| NAKAMURA Kohei \| ISHIKAWA Masako \| MINAMOTO Toshiko \| ISHIBASHI Tomoka \| YAMASHITA Hitomi \| IIDA Koji \| KYO Satoru
Journal
Date of Issued	published_at 2019-03-22

At-risk Internet addiction and related factors among junior high school teachers—based on a nationwide cross-sectional study in Japan

Creator	Iwaibara Ayumi \| FUKUDA Mari \| ツムラヒデキ \| Kanda Hideyuki
Journal
Date of Issued	published_at 2019-03-22

Diversity in the incidence and spectrum of organic acidemias, fatty acid oxidation disorders, and amino acid disorders in Asian countries: selective screening vs. expanded newborn screening

Creator	Shibata Naoaki \| Hasegawa Yuki \| YAMADA Kenji \| Kobayashi Hironori \| Purevsuren Jamiyan \| Yang Yanling \| Vu Chi Dung \| Nguyen Ngoc Khanh \| Ishwar C. Verma \| Sunita Bijarnia-Mahay \| Dong Hwan Lee \| Dau-Ming Niu \| Hoffmann Georg F. \| Shigematsu Yosuke \| Fukao Toshiyuki \| FUKUDA Seiji \| Taketani Takeshi \| Yamaguchi Seiji
Journal
Date of Issued	published_at 2019-03-22

Antifungal activity and mechanism of action of Ou-gon (Scutellaria root extract) components against pathogenic fungi

Creator	DA XIA \| Nishiyama Yayoi \| Duerna Tie \| Kyaw Zaw Hein \| Morita Eishin
Journal
Date of Issued	published_at 2019-03-20

Effect of the positional relationship between the interference screw and the tendon graft in the bone tunnel in ligament reconstruction

Creator	Aoki Akira \| Imade Shinji \| Uchio Yuji
Journal
Date of Issued	published_at 2019-03-06

博士（医学）