| File | |
| Title |
Phototropin-Inspired Chemoselective Synthesis of Unsymmetrical Disulfides: Aerobic Oxidative Heterocoupling of Thiols Using Flavin Photocatalysis
|
| Creator |
Oka Marina
Katsube Daichi
|
| Source Title |
Organic Letters
|
| Volume | 22 |
| Issue | 23 |
| Start Page | 9244 |
| End Page | 9248 |
| Journal Identifire |
ISSN 1523-7060
|
| Descriptions |
Inspired by the photochemical mechanism of a plant blue-light receptor, a unique flavin-based photocatalytic system was developed for the chemoselective heterocoupling of two different thiols, which enabled the facile synthesis of unsymmetrical disulfides. Owing to the redox- and photo-organocatalysis of flavin, the coupling reaction took place under mild metal-free conditions and visible light irradiation with the use of air, which is recognized as the ideal green oxidant.
|
| Subjects | |
| Language |
eng
|
| Resource Type | journal article |
| Publisher |
American Chemical Society
|
| Date of Issued | 2020-12-04 |
| Publish Type | Accepted Manuscript |
| Access Rights | open access |
| Relation |
[DOI] 10.1021/acs.orglett.0c03458
|
