| File | |
| Title |
Multicomponent Synthesis of Imidazo[1,2-a]pyridines: Aerobic Oxidative Formation of C–N and C–S Bonds by Flavin–Iodine-Coupled Organocatalysis
|
| Creator |
Okai Hayaki
Tanimoto Kazumasa
Ohkado Ryoma
|
| Source Title |
Organic Letters
|
| Volume | 22 |
| Issue | 20 |
| Start Page | 8002 |
| End Page | 8006 |
| Journal Identifire |
ISSN 1523-7060
|
| Descriptions |
Other
Herein, we report an aerobic oxidative C–N bond-forming process that enables the facile synthesis of imidazo[1,2-a]pyridines and takes advantage of a coupled organocatalytic system that uses flavin and iodine. Furthermore, the dual catalytic system can be applied to the one-pot, three-step synthesis of 3-thioimidazo[1,2-a]pyridines from aminopyridines, ketones, and thiols.
|
| Subjects |
Flavins
Chemical synthesis
Catalysts
Oxygen
Catalytic reactions
|
| Language |
eng
|
| Resource Type | journal article |
| Publisher |
American Chemical Society
|
| Date of Issued | 2020-10-16 |
| Publish Type | Accepted Manuscript |
| Access Rights | open access |
| Relation |
