Disulphide-reduced psoriasin is a human apoptosis-inducing broad-spectrum fungicide

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Volume 112 Issue 42 Page 13039-13044 published_at 2015-10-20
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Title
Disulphide-reduced psoriasin is a human apoptosis-inducing broad-spectrum fungicide
Creator
Hein Kyaw Zaw
Takahashi Hitoshi
Tsumori Toshiko
Yasui Yukihiko
Nanjoh Yasuko
Toga Tetsuo
Wu Zhihong
Groetzinger Joachim
Jung Sascha
Wehkamp Jan
Schroeder Bjoern O.
Schroeder Jens M.
Source Title
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 112
Issue 42
Start Page 13039
End Page 13044
Journal Identifire
ISSN 0027-8424
Subjects
antifungal; innate immunity; epithelial defense; psoriasin; S100A7 ( Other)
Language
eng
Resource Type journal article
Publisher
NATL ACAD SCIENCES
Date of Issued 2015-10-20
Access Rights metadata only access
Relation
[DOI] 10.1073/pnas.1511197112
[PMID] 26438863
Remark We thank S. Matsuki for discussions and technical help with the reactive oxygen species study; T. Yoneyama for technical help with scanning electron microscope and transmission electron microscope analyses; and Jutta Quitzau for HPLC. A. fumigatus Delta rodA were kindly provided by J. P. Latge (Pasteur Institute, Paris, France). This study was supported in part by the Otsuka Toshimi scholarship foundation for postgraduate support (to K.Z.H.); a European Union, European Research Council starting grant (to J.W. and B.O.S.); a Deutsche Forschungsgemeinschaft, Reinhart Koselleck high-risk project grant (to J.M.S.); and the Cluster of Excellence Inflammation at Interfaces (to J.G. and S.J.).